{"product_id":"sulindac-s2007","title":"Sulindac","description":"\u003cp\u003e\u003cstrong\u003eSulindac\u003c\/strong\u003e is an inhibitor of COX used in studies of NF-kB Signaling and Immune Signaling. It is especially relevant when investigators need a named chemical input and interpretable readouts connected to inflammatory transcriptional control and stress-responsive survival signaling and cytokine-mediated signaling and inflammatory effector responses in immunology, inflammation, and neuroscience models.\u003c\/p\u003e\n\n\u003cp\u003eBy inhibiting COX, Sulindac can be used to examine inflammatory transcriptional control and stress-responsive survival signaling and cytokine-mediated signaling and inflammatory effector responses. The enzyme annotation adds relevance to enzyme-activity assays, substrate-conversion studies, and mechanism profiling, together with downstream-response mapping in the same experimental setting. In immunology, inflammation, and neuroscience models, these readouts can be combined with viability, reporter, localization, biochemical conversion, or morphology endpoints to refine experimental interpretation.\u003c\/p\u003e\n\n\u003ch2\u003eResearch Applications\u003c\/h2\u003e\u003cul\u003e\n\u003cli\u003eTarget-focused assays involving COX\u003c\/li\u003e\n\u003cli\u003ePathway perturbation studies connected to NF-kB Signaling and Immune Signaling\u003c\/li\u003e\n\u003cli\u003eConcentration-response inhibition and target-dependence studies\u003c\/li\u003e\n\u003cli\u003eEnzyme-activity assays, substrate-conversion studies, and mechanism profiling\u003c\/li\u003e\n\u003c\/ul\u003e\n\n\u003cp\u003eOverall, Sulindac is appropriate when a defined chemical perturbant is needed to connect COX with measurable biochemical, transcriptional, electrophysiological, imaging, or phenotypic readouts in immunology, inflammation, and neuroscience models. This profile is suited to mechanistic follow-up, comparative profiling, and assay optimization under defined exposure conditions.\u003c\/p\u003e","brand":"Selleck Chemicals","offers":[{"title":"50 mg","offer_id":57805385793881,"sku":"S2007-50MG","price":144.0,"currency_code":"EUR","in_stock":true},{"title":"1 g","offer_id":57805385826649,"sku":"S2007-1G","price":658.0,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0923\/1011\/0553\/files\/Sulindac-Clinoril-chemical-structure-S2007.gif?v=1776174337","url":"https:\/\/absource.de\/products\/sulindac-s2007","provider":"Absource Diagnostics","version":"1.0","type":"link"}