{"product_id":"tbk1-ikkepsilon-in-2-s0425","title":"TBK1\/IKKε-IN-2","description":"\u003cp\u003e\u003cstrong\u003eTBK1\/IKKε-IN-2\u003c\/strong\u003e is an inhibitor of IKK used in studies of NF-kB Signaling and Immune Signaling. It is especially relevant when investigators need a named chemical input and interpretable readouts connected to inflammatory transcriptional control and stress-responsive survival signaling and cytokine-mediated signaling and inflammatory effector responses in immunology and inflammation models.\u003c\/p\u003e\n\n\u003cp\u003eBy inhibiting IKK, TBK1\/IKKε-IN-2 can be used to examine inflammatory transcriptional control and stress-responsive survival signaling and cytokine-mediated signaling and inflammatory effector responses. The signaling pathway modulator annotation adds relevance to pathway-reporter and mechanistic-phenotyping studies, together with downstream-response mapping in the same experimental setting. In immunology and inflammation models, these readouts can be combined with viability, reporter, localization, biochemical conversion, or morphology endpoints to refine experimental interpretation.\u003c\/p\u003e\n\n\u003ch2\u003eResearch Applications\u003c\/h2\u003e\u003cul\u003e\n\u003cli\u003eTarget-focused assays involving IKK\u003c\/li\u003e\n\u003cli\u003ePathway perturbation studies connected to NF-kB Signaling and Immune Signaling\u003c\/li\u003e\n\u003cli\u003eConcentration-response inhibition and target-dependence studies\u003c\/li\u003e\n\u003cli\u003ePathway-reporter and mechanistic-phenotyping studies\u003c\/li\u003e\n\u003c\/ul\u003e\n\n\u003cp\u003eOverall, TBK1\/IKKε-IN-2 is appropriate when a defined chemical perturbant is needed to connect IKK with measurable biochemical, transcriptional, electrophysiological, imaging, or phenotypic readouts in immunology and inflammation models. This profile is suited to mechanistic follow-up, comparative profiling, and assay optimization under defined exposure conditions.\u003c\/p\u003e","brand":"Selleck Chemicals","offers":[{"title":"5 mg","offer_id":57805114933593,"sku":"S0425-5MG","price":419.0,"currency_code":"EUR","in_stock":true},{"title":"25 mg","offer_id":57805114966361,"sku":"S0425-25MG","price":1294.0,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0923\/1011\/0553\/files\/s0425-tbk1ikke-in-1-chemical-structure.gif?v=1776172174","url":"https:\/\/absource.de\/products\/tbk1-ikkepsilon-in-2-s0425","provider":"Absource Diagnostics","version":"1.0","type":"link"}