{"product_id":"thz1-2hcl-s7549","title":"THZ1 2HCl","description":"\u003cp\u003e\u003cstrong\u003eTHZ1 2HCl\u003c\/strong\u003e is an inhibitor of CDK7 and CDK used in studies of Cell Cycle Regulation. It is especially relevant when investigators need a named chemical input and interpretable readouts connected to checkpoint control, mitotic progression, and proliferation timing in cancer, cell cycle, and cell signaling models.\u003c\/p\u003e\n\n\u003cp\u003eBy inhibiting CDK7 and CDK, THZ1 2HCl can be used to examine checkpoint control, mitotic progression, and proliferation timing. The kinase annotation adds relevance to biochemical kinase assays, phospho-signaling studies, and selectivity profiling, together with downstream-response mapping in the same experimental setting. In cancer, cell cycle, and cell signaling models, these readouts can be combined with viability, reporter, localization, biochemical conversion, or morphology endpoints to refine experimental interpretation.\u003c\/p\u003e\n\n\u003ch2\u003eResearch Applications\u003c\/h2\u003e\u003cul\u003e\n\u003cli\u003eTarget-focused assays involving CDK7 and CDK\u003c\/li\u003e\n\u003cli\u003ePathway perturbation studies connected to Cell Cycle Regulation\u003c\/li\u003e\n\u003cli\u003eConcentration-response inhibition and target-dependence studies\u003c\/li\u003e\n\u003cli\u003eBiochemical kinase assays, phospho-signaling studies, and selectivity profiling\u003c\/li\u003e\n\u003c\/ul\u003e\n\n\u003cp\u003eOverall, THZ1 2HCl is appropriate when a defined chemical perturbant is needed to connect CDK7 and CDK with measurable biochemical, transcriptional, electrophysiological, imaging, or phenotypic readouts in cancer, cell cycle, and cell signaling models. This profile is suited to mechanistic follow-up, comparative profiling, and assay optimization under defined exposure conditions.\u003c\/p\u003e","brand":"Selleck Chemicals","offers":[{"title":"5 mg","offer_id":57809494704473,"sku":"S7549-5MG","price":144.0,"currency_code":"EUR","in_stock":true},{"title":"25 mg","offer_id":57809494737241,"sku":"S7549-25MG","price":390.0,"currency_code":"EUR","in_stock":true},{"title":"1 g","offer_id":57809494770009,"sku":"S7549-1G","price":4904.0,"currency_code":"EUR","in_stock":true},{"title":"1 ml (10mM\/DMSO)","offer_id":57809494802777,"sku":"S7549-1ML\/DMSO","price":203.0,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0923\/1011\/0553\/files\/thz1-chemical-structure-s7549.gif?v=1776201548","url":"https:\/\/absource.de\/products\/thz1-2hcl-s7549","provider":"Absource Diagnostics","version":"1.0","type":"link"}