{"product_id":"tl13-112-e1846","title":"TL13-112","description":"\u003cp\u003e\u003cstrong\u003eTL13-112\u003c\/strong\u003e is a modulator of ALK used in studies of MAPK \/ ERK Signaling. In practice, this places the compound in experiments that measure mitogenic kinase cascades, proliferation control, and differentiation-linked signaling in cancer and cell signaling models.\u003c\/p\u003e\n\n\u003cp\u003eBy modulating ALK, TL13-112 can be used to examine mitogenic kinase cascades, proliferation control, and differentiation-linked signaling. The kinase annotation adds relevance to biochemical kinase assays, phospho-signaling studies, and selectivity profiling, together with downstream-response mapping in the same experimental setting. In cancer and cell signaling models, these readouts can be combined with viability, reporter, localization, biochemical conversion, or morphology endpoints to refine experimental interpretation.\u003c\/p\u003e\n\n\u003ch2\u003eResearch Applications\u003c\/h2\u003e\u003cul\u003e\n\u003cli\u003eTarget-focused assays involving ALK\u003c\/li\u003e\n\u003cli\u003ePathway perturbation studies connected to MAPK \/ ERK Signaling\u003c\/li\u003e\n\u003cli\u003eContext-dependent response profiling and mechanism comparison\u003c\/li\u003e\n\u003cli\u003eBiochemical kinase assays, phospho-signaling studies, and selectivity profiling\u003c\/li\u003e\n\u003c\/ul\u003e\n\n\u003cp\u003eOverall, TL13-112 is appropriate when a defined chemical perturbant is needed to connect ALK with measurable biochemical, transcriptional, electrophysiological, imaging, or phenotypic readouts in cancer and cell signaling models. This profile is suited to mechanistic follow-up, comparative profiling, and assay optimization under defined exposure conditions.\u003c\/p\u003e","brand":"Selleck Chemicals","offers":[{"title":"5 mg","offer_id":57804519309657,"sku":"E1846-5MG","price":193.0,"currency_code":"EUR","in_stock":true},{"title":"25 mg","offer_id":57804519342425,"sku":"E1846-25MG","price":488.0,"currency_code":"EUR","in_stock":true},{"title":"100 mg","offer_id":57804519375193,"sku":"E1846-100MG","price":953.0,"currency_code":"EUR","in_stock":true},{"title":"1 g","offer_id":57804519407961,"sku":"E1846-1G","price":2918.0,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0923\/1011\/0553\/files\/E1846-TL13-112-chemical-structure.png?v=1776167351","url":"https:\/\/absource.de\/products\/tl13-112-e1846","provider":"Absource Diagnostics","version":"1.0","type":"link"}