{"product_id":"tlr4-in-c34-s0822","title":"TLR4-IN-C34","description":"\u003cp\u003e\u003cstrong\u003eTLR4-IN-C34\u003c\/strong\u003e is an antagonist of TLR used in studies of NF-kB Signaling and Immune Signaling. It is especially relevant when investigators need a named chemical input and interpretable readouts connected to inflammatory transcriptional control and stress-responsive survival signaling and cytokine-mediated signaling and inflammatory effector responses in immunology and inflammation models.\u003c\/p\u003e\n\n\u003cp\u003eBy blocking TLR, TLR4-IN-C34 can be used to examine inflammatory transcriptional control and stress-responsive survival signaling and cytokine-mediated signaling and inflammatory effector responses. The immunomodulator annotation adds relevance to immune-cell activation, cytokine, and mediator assays, together with downstream-response mapping in the same experimental setting. In immunology and inflammation models, these readouts can be combined with viability, reporter, localization, biochemical conversion, or morphology endpoints to refine experimental interpretation.\u003c\/p\u003e\n\n\u003ch2\u003eResearch Applications\u003c\/h2\u003e\u003cul\u003e\n\u003cli\u003eTarget-focused assays involving TLR\u003c\/li\u003e\n\u003cli\u003ePathway perturbation studies connected to NF-kB Signaling and Immune Signaling\u003c\/li\u003e\n\u003cli\u003eReceptor-blockade and ligand-competition studies\u003c\/li\u003e\n\u003cli\u003eImmune-cell activation, cytokine, and mediator assays\u003c\/li\u003e\n\u003c\/ul\u003e\n\n\u003cp\u003eOverall, TLR4-IN-C34 is appropriate when a defined chemical perturbant is needed to connect TLR with measurable biochemical, transcriptional, electrophysiological, imaging, or phenotypic readouts in immunology and inflammation models. This profile is suited to mechanistic follow-up, comparative profiling, and assay optimization under defined exposure conditions.\u003c\/p\u003e","brand":"Selleck Chemicals","offers":[{"title":"Selleck \/ 5 mg","offer_id":57805148488025,"sku":"S0822-5MG","price":173.0,"currency_code":"EUR","in_stock":true},{"title":"Selleck \/ 25 mg","offer_id":57805148520793,"sku":"S0822-25MG","price":527.0,"currency_code":"EUR","in_stock":true},{"title":"Capsid \/ 5 mg","offer_id":58478374256985,"sku":"C07340-5MG","price":129.0,"currency_code":"EUR","in_stock":true},{"title":"Capsid \/ 25 mg","offer_id":58478374289753,"sku":"C07340-25MG","price":393.0,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0923\/1011\/0553\/files\/s0822-tlr4-in-c34-chemical-structure.gif?v=1776172538","url":"https:\/\/absource.de\/products\/tlr4-in-c34-s0822","provider":"Absource Diagnostics","version":"1.0","type":"link"}