{"product_id":"troglitazone-cs-045-s8432","title":"Troglitazone (CS-045)","description":"\u003cp\u003e\u003cstrong\u003eTroglitazone (CS-045)\u003c\/strong\u003e is an agonist of PPAR gamma and PPAR used in studies of Apoptosis and Autophagy and related signaling programs. It is especially relevant when investigators need a named chemical input and interpretable readouts connected to caspase-associated cell-death signaling and survival decisions and autophagic flux, lysosomal turnover, and stress adaptation in apoptosis, autophagy, and cancer models.\u003c\/p\u003e\n\n\u003cp\u003eBy activating PPAR gamma and PPAR, Troglitazone (CS-045) can be used to examine caspase-associated cell-death signaling and survival decisions and autophagic flux, lysosomal turnover, and stress adaptation. The nuclear receptor annotation adds relevance to reporter-gene, receptor-binding, and transcriptional assays, together with downstream-response mapping in the same experimental setting. In apoptosis, autophagy, and cancer models, these readouts can be combined with viability, reporter, localization, biochemical conversion, or morphology endpoints to refine experimental interpretation.\u003c\/p\u003e\n\n\u003ch2\u003eResearch Applications\u003c\/h2\u003e\u003cul\u003e\n\u003cli\u003eTarget-focused assays involving PPAR gamma and PPAR\u003c\/li\u003e\n\u003cli\u003ePathway perturbation studies connected to Apoptosis and Autophagy and related signaling programs\u003c\/li\u003e\n\u003cli\u003eAgonist-response and downstream signaling studies\u003c\/li\u003e\n\u003cli\u003eReporter-gene, receptor-binding, and transcriptional assays\u003c\/li\u003e\n\u003c\/ul\u003e\n\n\u003cp\u003eOverall, Troglitazone (CS-045) is appropriate when a defined chemical perturbant is needed to connect PPAR gamma and PPAR with measurable biochemical, transcriptional, electrophysiological, imaging, or phenotypic readouts in apoptosis, autophagy, and cancer models. This profile is suited to mechanistic follow-up, comparative profiling, and assay optimization under defined exposure conditions.\u003c\/p\u003e","brand":"Selleck Chemicals","offers":[{"title":"10 mg","offer_id":57809609621849,"sku":"S8432-10MG","price":144.0,"currency_code":"EUR","in_stock":true},{"title":"50 mg","offer_id":57809609654617,"sku":"S8432-50MG","price":439.0,"currency_code":"EUR","in_stock":true},{"title":"200 mg","offer_id":57809609687385,"sku":"S8432-200MG","price":1149.0,"currency_code":"EUR","in_stock":true},{"title":"1 g","offer_id":57809609720153,"sku":"S8432-1G","price":3921.0,"currency_code":"EUR","in_stock":true},{"title":"1 ml (10mM\/DMSO)","offer_id":57809609752921,"sku":"S8432-1ML\/DMSO","price":193.0,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0923\/1011\/0553\/files\/troglitazone-cs-045-chemical-structure-S8432.gif?v=1776202714","url":"https:\/\/absource.de\/products\/troglitazone-cs-045-s8432","provider":"Absource Diagnostics","version":"1.0","type":"link"}