{"product_id":"tst-antibody-sc-f3626","title":"TST Antibody","description":"\u003ch2\u003eAbout the Target\u003c\/h2\u003e\u003cp\u003eThiosulfate sulfurtransferase (TST), also known as rhodanese, is a mitochondrial enzyme that plays a pivotal role in cellular sulfur metabolism and redox regulation. It contains a highly conserved rhodanese domain, characterized by a five-stranded parallel β-sheet core flanked by α-helices. It features a catalytic cysteine residue (Cys-247 in humans) deeply embedded within its active site cleft. Depending on the literature source, TST may also be discussed as Thiosulfate sulfurtransferase and Rhodanese.\u003c\/p\u003e\u003cp\u003eReported cellular context includes mitochondrion, which can matter when signal is compared across treatments or changing cell states. Following TST across matched perturbations can help separate abundance effects from shifts in localization, complex assembly, or pathway state.\u003c\/p\u003e\u003ch2\u003eResearch Context\u003c\/h2\u003e\u003cp\u003eTST is commonly interpreted in the context of cancer and metabolism research, and readouts are often stronger when a study separates expression changes from compartment-level redistribution. When reported signal spans mitochondrion, a defined reference condition can make comparisons more interpretable across perturbations, passages, or replicate sets.\u003c\/p\u003e\u003cp\u003eConsider these angles when interpreting target-level changes:\u003c\/p\u003e\u003cul\u003e\n\u003cli\u003esignal enrichment within mitochondrion relative to the broader cellular background\u003c\/li\u003e\n\u003cli\u003echanges associated with proliferative state, oncogenic signaling, or treatment response\u003c\/li\u003e\n\u003cli\u003eresponses linked to nutrient status, mitochondrial state, or metabolic rewiring\u003c\/li\u003e\n\u003cli\u003eco-patterning with orthogonal markers and control conditions that clarify pathway state\u003c\/li\u003e\n\u003c\/ul\u003e\u003ch2\u003eVariant Considerations\u003c\/h2\u003e\u003cp\u003eIf your project spans exploratory questions, the regular version offers a balanced option for establishing baseline signal behavior for TST. This can help when protocols evolve over time and the goal is to compare experiments using a stable reference workflow.\u003c\/p\u003e\u003cp\u003eStandardize sampling time, control choice, and downstream analysis thresholds so apparent differences in TST reflect biology rather than handling. When interpreting TST, it is often useful to decide early whether the main question is overall abundance, compartmental enrichment, or context-dependent redistribution.\u003c\/p\u003e\u003cp\u003eFor multi-run studies, a shared reference condition can keep TST trends easier to compare across datasets. That kind of consistency is especially helpful when follow-up work expands to new perturbations, model systems, or longitudinal collections.\u003c\/p\u003e","brand":"Selleck Chemicals","offers":[{"title":"20 µl","offer_id":57578036724057,"sku":"F3626-20UL","price":199.0,"currency_code":"EUR","in_stock":true},{"title":"100 µl","offer_id":57578036756825,"sku":"F3626-100UL","price":489.0,"currency_code":"EUR","in_stock":true},{"title":"2 × 100 µl","offer_id":57578036789593,"sku":"F3626-2X100UL","price":729.0,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0923\/1011\/0553\/files\/F3626-IF.png?v=1773601346","url":"https:\/\/absource.de\/products\/tst-antibody-sc-f3626","provider":"Absource Diagnostics","version":"1.0","type":"link"}