{"product_id":"txnrd1-antibody-sc-f1144","title":"TXNRD1 Antibody","description":"\u003ch2\u003eAbout the Target\u003c\/h2\u003e\u003cp\u003eThioredoxin reductase 1 (TXNRD1) is a dimeric selenoenzyme that relies on NADPH and contains a flavin adenine dinucleotide (FAD) domain. It regulates the redox balance of cells by functioning as a fundamental antioxidant enzyme. The enzyme is present in the cytosol and nucleus and plays a vital role in regulating various cellular processes. Depending on the literature source, TXNRD1 may also be discussed as TRXR1.\u003c\/p\u003e\u003cp\u003eReported cellular context includes cytoplasm and nucleus, which can matter when signal is compared across treatments or changing cell states. Following TXNRD1 across matched perturbations can help separate abundance effects from shifts in localization, complex assembly, or pathway state.\u003c\/p\u003e\u003ch2\u003eResearch Context\u003c\/h2\u003e\u003cp\u003eTXNRD1 is commonly interpreted in the context of cancer, oxidative stress, and aging research, and readouts are often stronger when a study separates expression changes from compartment-level redistribution. When reported signal spans cytoplasm and nucleus, a defined reference condition can make comparisons more interpretable across perturbations, passages, or replicate sets.\u003c\/p\u003e\u003cp\u003eConsider these angles when interpreting target-level changes:\u003c\/p\u003e\u003cul\u003e\n\u003cli\u003eapparent redistribution between cytoplasm and nucleus across matched conditions\u003c\/li\u003e\n\u003cli\u003echanges associated with proliferative state, oncogenic signaling, or treatment response\u003c\/li\u003e\n\u003cli\u003eredox-associated shifts that may alter abundance, localization, or pathway coupling\u003c\/li\u003e\n\u003cli\u003econtext changes tied to cellular senescence, long-term stress adaptation, or tissue aging\u003c\/li\u003e\n\u003c\/ul\u003e\u003ch2\u003eVariant Considerations\u003c\/h2\u003e\u003cp\u003eIf your project spans exploratory questions, the regular version offers a balanced option for establishing baseline signal behavior for TXNRD1. This can help when protocols evolve over time and the goal is to compare experiments using a stable reference workflow.\u003c\/p\u003e\u003cp\u003eStandardize sampling time, control choice, and downstream analysis thresholds so apparent differences in TXNRD1 reflect biology rather than handling. When interpreting TXNRD1, it is often useful to decide early whether the main question is overall abundance, compartmental enrichment, or context-dependent redistribution.\u003c\/p\u003e\u003cp\u003eFor multi-run studies, a shared reference condition can keep TXNRD1 trends easier to compare across datasets. That kind of consistency is especially helpful when follow-up work expands to new perturbations, model systems, or longitudinal collections.\u003c\/p\u003e","brand":"Selleck Chemicals","offers":[{"title":"20 µl","offer_id":57577627746649,"sku":"F1144-20UL","price":149.0,"currency_code":"EUR","in_stock":true},{"title":"100 µl","offer_id":57577627779417,"sku":"F1144-100UL","price":329.0,"currency_code":"EUR","in_stock":true},{"title":"2 × 100 µl","offer_id":57577627812185,"sku":"F1144-2X100UL","price":489.0,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0923\/1011\/0553\/files\/F1144-IHC1.jpg?v=1773599346","url":"https:\/\/absource.de\/products\/txnrd1-antibody-sc-f1144","provider":"Absource Diagnostics","version":"1.0","type":"link"}