{"product_id":"uchl1-antibody-sc-f1137","title":"PGP9.5 Antibody","description":"\u003ch2\u003eAbout the Target\u003c\/h2\u003e\u003cp\u003eUCHL1 is a target of interest in many antibody-based workflows. PGP9. 5 (Protein gene product 9. 5, UCH-L1, PARK5) is a member of the ubiquitin carboxyl-terminal hydrolase family 1 (peptidase family C12) with a molecular weight of 27 kDa. Depending on the literature source, UCHL1 may also be discussed as PGP9.5 and Protein Gene Product 9.5.\u003c\/p\u003e\u003cp\u003eReported cellular context includes cytoplasm and endoplasmic reticulum, which can matter when signal is compared across treatments or changing cell states. Following UCHL1 across matched perturbations can help separate abundance effects from shifts in localization, complex assembly, or pathway state.\u003c\/p\u003e\u003ch2\u003eResearch Context\u003c\/h2\u003e\u003cp\u003eUCHL1 is commonly interpreted in the context of cancer, neuroscience, and apoptosis research, and readouts are often stronger when a study separates expression changes from compartment-level redistribution. When reported signal spans cytoplasm and endoplasmic reticulum, a defined reference condition can make comparisons more interpretable across perturbations, passages, or replicate sets.\u003c\/p\u003e\u003cp\u003eConsider these angles when interpreting target-level changes:\u003c\/p\u003e\u003cul\u003e\n\u003cli\u003eapparent redistribution between cytoplasm and endoplasmic reticulum across matched conditions\u003c\/li\u003e\n\u003cli\u003echanges associated with proliferative state, oncogenic signaling, or treatment response\u003c\/li\u003e\n\u003cli\u003ecompartment-specific patterns relevant to neuronal polarity, transport, or synaptic context\u003c\/li\u003e\n\u003cli\u003eseparation of survival-associated changes from stress or death-associated readouts\u003c\/li\u003e\n\u003c\/ul\u003e\u003ch2\u003eVariant Considerations\u003c\/h2\u003e\u003cp\u003eIf your project spans exploratory questions, the regular version offers a balanced option for establishing baseline signal behavior for UCHL1. This can help when protocols evolve over time and the goal is to compare experiments using a stable reference workflow.\u003c\/p\u003e\u003cp\u003eStandardize sampling time, control choice, and downstream analysis thresholds so apparent differences in UCHL1 reflect biology rather than handling. When interpreting UCHL1, it is often useful to decide early whether the main question is overall abundance, compartmental enrichment, or context-dependent redistribution.\u003c\/p\u003e\u003cp\u003eFor multi-run studies, a shared reference condition can keep UCHL1 trends easier to compare across datasets. That kind of consistency is especially helpful when follow-up work expands to new perturbations, model systems, or longitudinal collections.\u003c\/p\u003e","brand":"Selleck Chemicals","offers":[{"title":"20 µl","offer_id":57577624011097,"sku":"F1137-20UL","price":149.0,"currency_code":"EUR","in_stock":true},{"title":"100 µl","offer_id":57577624043865,"sku":"F1137-100UL","price":359.0,"currency_code":"EUR","in_stock":true},{"title":"2 × 100 µl","offer_id":57577624076633,"sku":"F1137-2X100UL","price":539.0,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0923\/1011\/0553\/files\/F1137-IF.png?v=1773599330","url":"https:\/\/absource.de\/products\/uchl1-antibody-sc-f1137","provider":"Absource Diagnostics","version":"1.0","type":"link"}