{"product_id":"vanzacaftor-vx-121-e1701","title":"Vanzacaftor (VX-121)","description":"\u003cp\u003e\u003cstrong\u003eVanzacaftor (VX-121)\u003c\/strong\u003e is a research compound associated with CFTR and is relevant to studies of ion-channel pharmacology. It is especially relevant when investigators need a named chemical input and interpretable readouts connected to ion conductance, membrane potential, and electrophysiological responses in cell signaling models.\u003c\/p\u003e\n\n\u003cp\u003eThe current annotation links Vanzacaftor (VX-121) to CFTR, supporting target-focused studies that measure ion conductance, membrane potential, and electrophysiological responses without assigning a more specific primary mechanism than the dataset provides. This target class is commonly examined through electrophysiology, ion-flux, and membrane-potential studies, together with downstream-response mapping. In cell signaling models, these readouts can be combined with viability, reporter, localization, biochemical conversion, or morphology endpoints to refine experimental interpretation.\u003c\/p\u003e\n\n\u003ch2\u003eResearch Applications\u003c\/h2\u003e\u003cul\u003e\n\u003cli\u003eTarget-focused assays involving CFTR\u003c\/li\u003e\n\u003cli\u003eElectrophysiology, ion-flux, and membrane-potential studies\u003c\/li\u003e\n\u003cli\u003ePhenotypic profiling in cell signaling models\u003c\/li\u003e\n\u003cli\u003eCombination studies with orthogonal perturbagens\u003c\/li\u003e\n\u003c\/ul\u003e\n\n\u003cp\u003eOverall, Vanzacaftor (VX-121) is appropriate when a defined chemical perturbant is needed to connect CFTR with measurable biochemical, transcriptional, electrophysiological, imaging, or phenotypic readouts in cell signaling models. This profile is suited to mechanistic follow-up, comparative profiling, and assay optimization under defined exposure conditions.\u003c\/p\u003e","brand":"Selleck Chemicals","offers":[{"title":"1 mg","offer_id":57804438405465,"sku":"E1701-1MG","price":193.0,"currency_code":"EUR","in_stock":true},{"title":"5 mg","offer_id":57804438438233,"sku":"E1701-5MG","price":341.0,"currency_code":"EUR","in_stock":true},{"title":"25 mg","offer_id":57804438471001,"sku":"E1701-25MG","price":763.0,"currency_code":"EUR","in_stock":true},{"title":"100 mg","offer_id":57804438503769,"sku":"E1701-100MG","price":1739.0,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0923\/1011\/0553\/files\/E1701-Vanzacaftor-chemical-structure.png?v=1776167168","url":"https:\/\/absource.de\/products\/vanzacaftor-vx-121-e1701","provider":"Absource Diagnostics","version":"1.0","type":"link"}