{"product_id":"vcam1-cd106-antibody-western-blot-validated","title":"VCAM1 (CD106) Antibody - Western Blot Validated","description":"\u003ch2\u003eBiological Background\u003c\/h2\u003e\n\u003cp\u003eFor consistent comparison across experiments, use this antibody to examine VCAM1 with a repeatable workflow. VCAM1 is a contact-site protein that shapes barrier properties and signaling at the cell surface. Use matched handling so differences reflect biology rather than processing.\u003c\/p\u003e\n\u003cp\u003eFollowing VCAM1 across perturbations can help separate expression effects from compartment shifts.\u003c\/p\u003e\n\u003ch2\u003eUse in the Laboratory\u003c\/h2\u003e\n\u003cp\u003eJunction proteins are frequently analyzed during differentiation, stress responses, and changes in cell polarity. Define inclusion criteria and controls early so replicate sets remain interpretable as the dataset grows. Blood-brain barrier models often monitor junction regulation alongside permeability-focused measurements.\u003c\/p\u003e\n\u003cp\u003eMany targets show context-dependent localization, so comparisons across matched conditions can reveal meaningful patterns.\u003c\/p\u003e\n\u003cp\u003eTo keep datasets interpretable, labs often document:\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003eco-localization patterns with cytoskeletal elements\u003c\/li\u003e\n\u003cli\u003esubcellular redistribution at contact sites versus cytoplasm\u003c\/li\u003e\n\u003cli\u003echanges in complex assembly with scaffold or adaptor proteins\u003c\/li\u003e\n\u003cli\u003ecomparative profiling across cell states or perturbations\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch2\u003eVersion Notes\u003c\/h2\u003e\n\u003cp\u003eWhen samples are prepared in reducing conditions, some epitopes become more accessible; this version is designed with that context in mind. If your study compares multiple conditions, keep acquisition and processing settings stable to avoid confounding. A brief pilot run can help set exposure ranges and reduce reruns later.\u003c\/p\u003e\n\u003cp\u003eFor challenging targets, pairing VCAM1 measurements with a second marker can clarify whether differences arise from regulation, redistribution, or shifts in cell composition within the sample.\u003c\/p\u003e\n\u003cp\u003eFor multi-run studies, the denaturing-format option helps keep VCAM1 trends comparable from experiment to experiment.\u003c\/p\u003e","brand":"BiCell Scientific","offers":[{"title":"50 µl \/ No Blocker","offer_id":58102156656985,"sku":"01002-WB-50UL","price":500.0,"currency_code":"EUR","in_stock":true},{"title":"50 µl \/ 1 µg","offer_id":58102156689753,"sku":"01002-WB-50UL+1UG","price":569.0,"currency_code":"EUR","in_stock":true},{"title":"50 µl \/ 10 µg","offer_id":58102156722521,"sku":"01002-WB-50UL+10UG","price":619.0,"currency_code":"EUR","in_stock":true},{"title":"200 µl \/ No Blocker","offer_id":58102156755289,"sku":"01002-WB-200UL","price":1110.0,"currency_code":"EUR","in_stock":true},{"title":"200 µl \/ 1 µg","offer_id":58102156788057,"sku":"01002-WB-200UL+1UG","price":1179.0,"currency_code":"EUR","in_stock":true},{"title":"200 µl \/ 10 µg","offer_id":58102156820825,"sku":"01002-WB-200UL+10UG","price":1229.0,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0923\/1011\/0553\/files\/vcam-neural-e14-sharpened.jpg?v=1779282880","url":"https:\/\/absource.de\/products\/vcam1-cd106-antibody-western-blot-validated","provider":"Absource Diagnostics","version":"1.0","type":"link"}