{"product_id":"wp1066-s2796","title":"WP1066","description":"\u003cp\u003e\u003cstrong\u003eWP1066\u003c\/strong\u003e is an inhibitor of JAK2 and STAT used in studies of JAK-STAT Signaling and Apoptosis. In practice, this places the compound in experiments that measure cytokine-responsive transcriptional signaling and immune regulation and caspase-associated cell-death signaling and survival decisions in apoptosis, cancer, and cell signaling models.\u003c\/p\u003e\n\n\u003cp\u003eBy inhibiting JAK2 and STAT, WP1066 can be used to examine cytokine-responsive transcriptional signaling and immune regulation and caspase-associated cell-death signaling and survival decisions. The kinase annotation adds relevance to biochemical kinase assays, phospho-signaling studies, and selectivity profiling, together with downstream-response mapping in the same experimental setting. In apoptosis, cancer, and cell signaling models, these readouts can be combined with viability, reporter, localization, biochemical conversion, or morphology endpoints to refine experimental interpretation.\u003c\/p\u003e\n\n\u003ch2\u003eResearch Applications\u003c\/h2\u003e\u003cul\u003e\n\u003cli\u003eTarget-focused assays involving JAK2 and STAT\u003c\/li\u003e\n\u003cli\u003ePathway perturbation studies connected to JAK-STAT Signaling and Apoptosis\u003c\/li\u003e\n\u003cli\u003eConcentration-response inhibition and target-dependence studies\u003c\/li\u003e\n\u003cli\u003eBiochemical kinase assays, phospho-signaling studies, and selectivity profiling\u003c\/li\u003e\n\u003c\/ul\u003e\n\n\u003cp\u003eOverall, WP1066 is appropriate when a defined chemical perturbant is needed to connect JAK2 and STAT with measurable biochemical, transcriptional, electrophysiological, imaging, or phenotypic readouts in apoptosis, cancer, and cell signaling models. This profile is suited to mechanistic follow-up, comparative profiling, and assay optimization under defined exposure conditions.\u003c\/p\u003e","brand":"Selleck Chemicals","offers":[{"title":"10 mg","offer_id":57805723140441,"sku":"S2796-10MG","price":144.0,"currency_code":"EUR","in_stock":true},{"title":"1 g","offer_id":57805723173209,"sku":"S2796-1G","price":2938.0,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0923\/1011\/0553\/files\/WP1066-chemical-structure-s2796.gif?v=1776175721","url":"https:\/\/absource.de\/products\/wp1066-s2796","provider":"Absource Diagnostics","version":"1.0","type":"link"}