{"product_id":"wy-14643-pirinixic-acid-s8029","title":"WY-14643 (Pirinixic Acid)","description":"\u003cp\u003e\u003cstrong\u003eWY-14643 (Pirinixic Acid)\u003c\/strong\u003e is an activator of PPAR and PPAR alpha used in studies of Hormone Signaling and Metabolic Signaling. It is especially relevant in endocrinology and metabolism models, where defined compound exposure can be linked to ligand-dependent transcriptional programs and endocrine regulation and metabolic regulation, energy sensing, and enzyme-linked homeostasis.\u003c\/p\u003e\n\n\u003cp\u003eBy activating PPAR and PPAR alpha, WY-14643 (Pirinixic Acid) can be used to examine ligand-dependent transcriptional programs and endocrine regulation and metabolic regulation, energy sensing, and enzyme-linked homeostasis. The nuclear receptor annotation adds relevance to reporter-gene, receptor-binding, and transcriptional assays, together with downstream-response mapping in the same experimental setting. In endocrinology and metabolism models, these readouts can be combined with viability, reporter, localization, biochemical conversion, or morphology endpoints to refine experimental interpretation.\u003c\/p\u003e\n\n\u003ch2\u003eResearch Applications\u003c\/h2\u003e\u003cul\u003e\n\u003cli\u003eTarget-focused assays involving PPAR and PPAR alpha\u003c\/li\u003e\n\u003cli\u003ePathway perturbation studies connected to Hormone Signaling and Metabolic Signaling\u003c\/li\u003e\n\u003cli\u003eGain-of-function pathway-activation studies\u003c\/li\u003e\n\u003cli\u003eReporter-gene, receptor-binding, and transcriptional assays\u003c\/li\u003e\n\u003c\/ul\u003e\n\n\u003cp\u003eOverall, WY-14643 (Pirinixic Acid) is appropriate when a defined chemical perturbant is needed to connect PPAR and PPAR alpha with measurable biochemical, transcriptional, electrophysiological, imaging, or phenotypic readouts in endocrinology and metabolism models. This profile is suited to mechanistic follow-up, comparative profiling, and assay optimization under defined exposure conditions.\u003c\/p\u003e","brand":"Selleck Chemicals","offers":[{"title":"50 mg","offer_id":57809570791769,"sku":"S8029-50MG","price":144.0,"currency_code":"EUR","in_stock":true},{"title":"250 mg","offer_id":57809570824537,"sku":"S8029-250MG","price":363.0,"currency_code":"EUR","in_stock":true},{"title":"1 g","offer_id":57809570857305,"sku":"S8029-1G","price":658.0,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0923\/1011\/0553\/files\/WY-14643-chemical-structure-s8029.gif?v=1776202216","url":"https:\/\/absource.de\/products\/wy-14643-pirinixic-acid-s8029","provider":"Absource Diagnostics","version":"1.0","type":"link"}