{"product_id":"xav-939-s1180","title":"XAV-939","description":"\u003cp\u003e\u003cstrong\u003eXAV-939\u003c\/strong\u003e is an inhibitor of PARP used in studies of NF-kB Signaling and Immune Signaling and related signaling programs. In practice, this places the compound in experiments that measure inflammatory transcriptional control and stress-responsive survival signaling and cytokine-mediated signaling and inflammatory effector responses in cancer, developmental biology, and dna damage \/ repair models.\u003c\/p\u003e\n\n\u003cp\u003eBy inhibiting PARP, XAV-939 can be used to examine inflammatory transcriptional control and stress-responsive survival signaling and cytokine-mediated signaling and inflammatory effector responses. The enzyme annotation adds relevance to enzyme-activity assays, substrate-conversion studies, and mechanism profiling, together with downstream-response mapping in the same experimental setting. In cancer, developmental biology, and dna damage \/ repair models, these readouts can be combined with viability, reporter, localization, biochemical conversion, or morphology endpoints to refine experimental interpretation.\u003c\/p\u003e\n\n\u003ch2\u003eResearch Applications\u003c\/h2\u003e\u003cul\u003e\n\u003cli\u003eTarget-focused assays involving PARP\u003c\/li\u003e\n\u003cli\u003ePathway perturbation studies connected to NF-kB Signaling and Immune Signaling and related signaling programs\u003c\/li\u003e\n\u003cli\u003eConcentration-response inhibition and target-dependence studies\u003c\/li\u003e\n\u003cli\u003eEnzyme-activity assays, substrate-conversion studies, and mechanism profiling\u003c\/li\u003e\n\u003c\/ul\u003e\n\n\u003cp\u003eOverall, XAV-939 is appropriate when a defined chemical perturbant is needed to connect PARP with measurable biochemical, transcriptional, electrophysiological, imaging, or phenotypic readouts in cancer, developmental biology, and dna damage \/ repair models. This profile is suited to mechanistic follow-up, comparative profiling, and assay optimization under defined exposure conditions.\u003c\/p\u003e","brand":"Selleck Chemicals","offers":[{"title":"10 mg","offer_id":57805238665561,"sku":"S1180-10MG","price":144.0,"currency_code":"EUR","in_stock":true},{"title":"25 mg","offer_id":57805238698329,"sku":"S1180-25MG","price":242.0,"currency_code":"EUR","in_stock":true},{"title":"50 mg","offer_id":57805238731097,"sku":"S1180-50MG","price":363.0,"currency_code":"EUR","in_stock":true},{"title":"1 g","offer_id":57805238763865,"sku":"S1180-1G","price":1444.0,"currency_code":"EUR","in_stock":true},{"title":"1 ml (10mM\/DMSO)","offer_id":57805238796633,"sku":"S1180-1ML\/DMSO","price":193.0,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0923\/1011\/0553\/files\/s1180-xav-939-chemical-structure.png?v=1776173051","url":"https:\/\/absource.de\/products\/xav-939-s1180","provider":"Absource Diagnostics","version":"1.0","type":"link"}