{"product_id":"zelavespib-pu-h71-s8039","title":"Zelavespib (PU-H71)","description":"\u003cp\u003e\u003cstrong\u003eZelavespib (PU-H71)\u003c\/strong\u003e is an inhibitor of HSP90 used in studies of target-focused biology. It is especially relevant when investigators need a named chemical input and interpretable readouts connected to annotated target biology and downstream cellular responses in cancer and protein homeostasis models.\u003c\/p\u003e\n\n\u003cp\u003eBy inhibiting HSP90, Zelavespib (PU-H71) can be used to examine annotated target biology and downstream cellular responses. That positioning is consistent with concentration-response inhibition and target-dependence studies and with follow-up studies that compare concentration-dependent responses across orthogonal assay formats. In cancer and protein homeostasis models, these readouts can be combined with viability, reporter, localization, biochemical conversion, or morphology endpoints to refine experimental interpretation.\u003c\/p\u003e\n\n\u003ch2\u003eResearch Applications\u003c\/h2\u003e\u003cul\u003e\n\u003cli\u003eTarget-focused assays involving HSP90\u003c\/li\u003e\n\u003cli\u003eConcentration-response inhibition and target-dependence studies\u003c\/li\u003e\n\u003cli\u003ePhenotypic profiling in cancer and protein homeostasis models\u003c\/li\u003e\n\u003cli\u003eCombination studies with orthogonal perturbagens\u003c\/li\u003e\n\u003c\/ul\u003e\n\n\u003cp\u003eOverall, Zelavespib (PU-H71) is appropriate when a defined chemical perturbant is needed to connect HSP90 with measurable biochemical, transcriptional, electrophysiological, imaging, or phenotypic readouts in cancer and protein homeostasis models. This profile is suited to mechanistic follow-up, comparative profiling, and assay optimization under defined exposure conditions.\u003c\/p\u003e","brand":"Selleck Chemicals","offers":[{"title":"10 mg","offer_id":57809572921689,"sku":"S8039-10MG","price":144.0,"currency_code":"EUR","in_stock":true},{"title":"100 mg","offer_id":57809572954457,"sku":"S8039-100MG","price":667.0,"currency_code":"EUR","in_stock":true},{"title":"1 g","offer_id":57809572987225,"sku":"S8039-1G","price":2938.0,"currency_code":"EUR","in_stock":true},{"title":"1 ml (10mM\/DMSO)","offer_id":57809573019993,"sku":"S8039-1ML\/DMSO","price":193.0,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0923\/1011\/0553\/files\/PU-H71-chemical-structure-s8039.gif?v=1776202239","url":"https:\/\/absource.de\/products\/zelavespib-pu-h71-s8039","provider":"Absource Diagnostics","version":"1.0","type":"link"}