{"product_id":"zosuquidar-e8180","title":"Zosuquidar","description":"\u003cp\u003e\u003cstrong\u003eZosuquidar\u003c\/strong\u003e is an inhibitor of P-gp used in studies of transporter biology. In practice, this places the compound in experiments that measure substrate uptake, efflux, and membrane-transport control in cancer and infectious disease models. Dose-response comparison, orthogonal validation, and secondary assay follow-up can further sharpen mechanistic interpretation.\u003c\/p\u003e\n\n\u003cp\u003eBy inhibiting P-gp, Zosuquidar can be used to examine substrate uptake, efflux, and membrane-transport control. This target class is commonly examined through transport, uptake\/efflux, and permeability assays, together with downstream-response mapping. In cancer and infectious disease models, these readouts can be combined with viability, reporter, localization, biochemical conversion, or morphology endpoints to refine experimental interpretation.\u003c\/p\u003e\n\n\u003ch2\u003eResearch Applications\u003c\/h2\u003e\u003cul\u003e\n\u003cli\u003eTarget-focused assays involving P-gp\u003c\/li\u003e\n\u003cli\u003eConcentration-response inhibition and target-dependence studies\u003c\/li\u003e\n\u003cli\u003eTransport, uptake\/efflux, and permeability assays\u003c\/li\u003e\n\u003cli\u003ePhenotypic profiling in cancer and infectious disease models\u003c\/li\u003e\n\u003c\/ul\u003e\n\n\u003cp\u003eOverall, Zosuquidar is appropriate when a defined chemical perturbant is needed to connect P-gp with measurable biochemical, transcriptional, electrophysiological, imaging, or phenotypic readouts in cancer and infectious disease models. This profile is suited to mechanistic follow-up, comparative profiling, and assay optimization under defined exposure conditions.\u003c\/p\u003e","brand":"Selleck Chemicals","offers":[{"title":"Default Title","offer_id":57818755596633,"sku":"E8180","price":0.0,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0923\/1011\/0553\/files\/e8180-zosuquidar-chemical-structure-tube.png?v=1776276314","url":"https:\/\/absource.de\/products\/zosuquidar-e8180","provider":"Absource Diagnostics","version":"1.0","type":"link"}