11-beta-HSD1 (HSD11B1) Antibody
Catalog-Number:
52041
Storage
-20°C
Description
Anti-11-beta-HSD1 (HSD11B1) antibody is validated on mouse tissue and recommended for immunofluorescence labeling, IHC, or western blot of materials from human and rodent tissues. 11-beta-Hydroxysteroid dehydrogenase type 1 (HSD1), also known as cortisone reductase, is an NADPH-dependent enzyme that is encoded by the HSD11B1 gene in human. 11-beta-HSD1 reduces cortisone to the active hormone cortisol that activates glucocorticoid receptors. 11-beta-HSD1 is highly expressed in key metabolic tissues including liver, adipose tissue, and the central nervous system.
| Application: | Immunofluorescence, Immunohistochemistry, Western Blot |
|---|---|
| Clonality: | Polyclonal |
| Concentration: | 0.25 mg/ml |
| Conjugation: | Unconjugated |
| Host: | Rat |
| Immunogen: | Synthetic peptide (16-aa) derived from the C-terminal region of mouse HSD11B1 protein |
| Isotype: | IgG |
| Purification: | Affinity Chromatography |
| Reactivity: | Human, Mouse, Rat |
| Species Homology: | Synthetic peptide sequence is identical to rat sequence (showing 81.3% homology to human sequence) |
| Storage: | -20°C |
| Storage Buffer: | PBS, pH 7.2, 0.1% Sodium Azide |