Actinin alpha-4 (ACTN4) Antibody
Catalog-Number:
00174
Storage
-20°C
Description
Anti-Actinin alpha-4 (ACTN4) antibody is validated on mouse tissue and recommended for immunofluorescence labeling, IHC, or western blot of materials from rodent and human tissues. Actinin alpha-4 is encoded by the ACTN4 gene in human. Actinin alpha-4 is an actin-binding protein. In nonmuscle cells, actinin alpha-4 is concentrated along the microfilament bundles near the adherens junctions. Actinin alpha-4 contains actin binding domain, spectrin domain and EF-hand domain. Actinin alpha-4 is highly expressed by the glomerular podocytes. Mutations in actinin alpha-4 cause focal segmental glomerulosclerosis (FSGS) (OMIM 603278).
| Application: | Immunofluorescence, Immunohistochemistry, Western Blot |
|---|---|
| Clonality: | Polyclonal |
| Concentration: | 0.25 mg/ml |
| Conjugation: | Unconjugated |
| Host: | Rabbit |
| Immunogen: | Synthetic peptide (18-aa) derived from the C-terminal region of human actinin alpha-4 protein |
| Isotype: | IgG |
| Purification: | Affinity Chromatography |
| Reactivity: | Human, Mouse, Rat |
| Species Homology: | Synthetic peptide sequence is identical to mouse or rat sequence |
| Storage: | -20°C |
| Storage Buffer: | PBS, pH 7.2, 0.1% Sodium Azide |