CACNA1E (Cav2.3) Antibody
Description
Anti-CACNA1E (Cav2.3) antibody is validated on mouse tissue and recommended for immunofluorescence labeling, IHC, or western blot of materials from rodent and human tissues. Calcium voltage-gated channel subunit alpha 1E, also known as Cav2.3, is a R-type voltage-dependent calcium channel that is encoded by the CACNA1E gene in human. The alpha-1 subunit consists of 24 transmembrane segments and forms the pore through which ions pass into the cell. The calcium channel consists of a complex of alpha-1, alpha-2/delta, beta, and gamma subunits in a 1:1:1:1 ratio. Cav2.3 is strongly expressed in the neural tissues such as cortex, hippocampus, striatum, amygdala and interpeduncular nucleus.
| Application: | Immunofluorescence, Immunohistochemistry, Western Blot |
|---|---|
| Clonality: | Polyclonal |
| Concentration: | 0.25 mg/ml |
| Conjugation: | Unconjugated |
| Host: | Rabbit |
| Immunogen: | Synthetic peptide (16-aa) derived from the N-terminal region of mouse Cav2.3 protein |
| Isotype: | IgG |
| Purification: | Affinity Chromatography |
| Reactivity: | Human, Mouse, Rat |
| Species Homology: | Synthetic peptide sequence is identical to rat sequence (showing 87.5% homology to human sequence) |
| Storage: | -20°C |
| Storage Buffer: | PBS, pH 7.2, 0.1% Sodium Azide |