Cadherin-16 (Cdh16) Antibody
Description
Anti-Cadherin-16 (Cdh16) antibody is validated on mouse tissue and recommended for immunofluorescence labeling, IHC, or western blot of materials from rodent and human tissues. Cadherin-16 is a protein that is encoded by the Cdh16 gene in human. Cadherin-16 is also known as kidney specific cadherin (Ksp-cadherin). Cadherin-16 belongs to the classic cadherin protein superfamily. The cadherin protein features an amino-terminal extracellular domain or ectodomain or EC domain that is followed by a transmembrane domain and a carboxyl-terminal intracellular domain. The cadherin ectodomain plays an adhesive role whereas the intracellular domain mediates cadherin-catenin interactions. Cadherin-16 is exclusively expressed in the kidney, where it plays a vital role in kidney development.
| Application: | Immunofluorescence, Immunohistochemistry, Western Blot |
|---|---|
| Clonality: | Polyclonal |
| Concentration: | 0.25 mg/ml |
| Conjugation: | Unconjugated |
| Host: | Rabbit |
| Immunogen: | Synthetic peptide (18-aa) derived from the C-terminal region of mouse Cadherin-16 protein |
| Isotype: | IgG |
| Purification: | Affinity Chromatography |
| Reactivity: | Human, Mouse, Rat |
| Species Homology: | Synthetic peptide sequence is identical to rat sequence (showing 88.9% homology to human sequence) |
| Storage: | -20°C |
| Storage Buffer: | PBS, pH 7.2, 0.1% Sodium Azide |