Claudin-10 (CLDN10) Antibody
Description
Anti-Claudin-10 (CLDN10) antibody is validated on mouse tissue and can be used for immunofluorescence labeling, IHC, or western blot of materials from rodent and human tissues. Claudin-10 is a protein that is encoded by the CLDN10 gene in human. Claudin-10 belongs to the Claudin protein superfamily. Claudins are tetraspan proteins making the tight junction. Claudins have four transmembrane domains, two extracellular loops (ECLs: ECL1 and ECL2), amino- and carboxyl-terminal cytoplasmic domains, and a short cytoplasmic motif. Claudin-10 has two splicing isoforms: 10a and 10b, which differ in the first transmembrane domain and the first extracellular loop. Claudin-10 is highly expressed by the epithelial cells in the intestines and the kidney. Note that this antibody will recognize both Claudin-10a and -10b proteins.
| Application: | Immunofluorescence, Immunohistochemistry, Western Blot |
|---|---|
| Clonality: | Polyclonal |
| Concentration: | 0.25 mg/ml |
| Conjugation: | Unconjugated |
| Host: | Rabbit |
| Immunogen: | Synthetic peptide (14-aa) derived from the C-terminal region of human Claudin-10 protein |
| Isotype: | IgG |
| Purification: | Affinity Chromatography |
| Reactivity: | Human, Mouse, Rat |
| Species Homology: | Synthetic peptide sequence is identical to mouse or rat sequence |
| Storage: | -20°C |
| Storage Buffer: | PBS, pH 7.2, 0.1% Sodium Azide |