Claudin-2 (CLDN2) Monoclonal Antibody (G2 Clone)
Description
Anti-Claudin-2 (CLDN2) monoclonal antibody (G2 clone) is validated on mouse tissues and can be used for immunofluorescence labeling, IHC, or western blot of materials from rodent and human tissues. The G2 clone is particularly suited for IF application on cryosections as well as western blot. Claudin-2 is a protein that is encoded by the CLDN2 gene in human. Claudin-2 belongs to the Claudin protein superfamily. Claudins are tetraspan proteins making the tight junction. Claudins have four transmembrane domains, two extracellular loops (ECLs: ECL1 and ECL2), amino- and carboxyl-terminal cytoplasmic domains, and a short cytoplasmic motif. Claudin-2 is primarily expressed in intestinal crypts and is strongly upregulated in inflammatory diseases of the intestines.
| Application: | Immunofluorescence, Immunohistochemistry, Western Blot |
|---|---|
| Clonality: | Monoclonal |
| Concentration: | 0.25 mg/ml |
| Conjugation: | Unconjugated |
| Host: | Mouse |
| Immunogen: | Synthetic peptide (13-aa) derived from the C-terminal region of human Claudin-2 protein |
| Isotype: | IgG |
| Purification: | Affinity Chromatography |
| Reactivity: | Human, Mouse, Rat |
| Species Homology: | Synthetic peptide sequence is identical to mouse or rat sequence |
| Storage: | -20°C |
| Storage Buffer: | PBS, pH 7.2, 0.1% Sodium Azide |