FGFR4 (CD334) Antibody
Description
Anti-FGFR4 (CD334) antibody is validated on mouse tissue and recommended for immunofluorescence labeling, IHC, or western blot of materials from rodent tissues. Fibroblast growth factor receptor 4, also known as CD334, is a membrane protein that is encoded by the FGFR4 gene in human. The FGFR4 protein consists of an extracellular region, composed of three immunoglobulin-like domains, a single hydrophobic membrane-spanning segment, and a cytoplasmic tyrosine kinase domain. FGFR4 is involved in the regulation of several pathways, including cell proliferation, cell differentiation, cell migration, lipid metabolism, bile acid biosynthesis, vitamin D metabolism, glucose uptake, and phosphate homeostasis.
| Application: | Immunofluorescence, Immunohistochemistry, Western Blot |
|---|---|
| Clonality: | Polyclonal |
| Concentration: | 0.25 mg/ml |
| Conjugation: | Unconjugated |
| Host: | Rat |
| Immunogen: | Synthetic peptide (16-aa) derived from the C-terminal region of mouse FGFR4 protein |
| Isotype: | IgG |
| Purification: | Affinity Chromatography |
| Reactivity: | Mouse, Rat |
| Species Homology: | Synthetic peptide sequence is identical to rat sequence (showing 56.3% homology to human sequence) |
| Storage: | -20°C |
| Storage Buffer: | PBS, pH 7.2, 0.1% Sodium Azide |