GABRA1 Antibody
Description
Anti-GABRA1 antibody is validated on mouse tissue and can be used for immunofluorescence labeling, IHC, or western blot of materials from rodent and human tissues. Gamma-aminobutyric acid type A (GABA-A) receptor subunit alpha-1 is a protein that is encoded by the GABRA1 gene in human. GABA-A is the receptor protein that, once bound to its ligand, GABA, transmits inhibitory signals in the mammalian brain. GABA-A receptor protein functions as a ligand-gated chloride channel. GABA-A receptors are pentameric, consisting of proteins from several subunit classes: alpha, beta, gamma, delta and rho. Mutations in GABRA1 cause juvenile myoclonic epilepsy and childhood absence epilepsy type 4 in man.
| Application: | Immunofluorescence, Immunohistochemistry, Western Blot |
|---|---|
| Clonality: | Polyclonal |
| Concentration: | 0.25 mg/ml |
| Conjugation: | Unconjugated |
| Host: | Rabbit |
| Immunogen: | Synthetic peptide (13-aa) derived from the N-terminal extracellular region of mouse GABRA1 protein |
| Isotype: | IgG |
| Purification: | Affinity Chromatography |
| Reactivity: | Human, Mouse, Rat |
| Species Homology: | Synthetic peptide sequence is identical to rat sequence (showing 92.9% homology to human sequence) |
| Storage: | -20°C |
| Storage Buffer: | PBS, pH 7.2, 0.1% Sodium Azide |