GRIA2 (GluR2 or GluA2) Antibody
Description
Anti-GRIA2 (GluR2 or GluA2) antibody is validated on mouse tissue and can be used for immunofluorescence labeling, IHC, or western blot of materials from rodent and human tissues. Glutamate ionotropic receptor AMPA type subunit 2 (GRIA2), also known as Glutamate receptor R2 or A2 (GluR2 or GluA2) is encoded by the GRIA2 gene in human. Glutamate receptors are the predominant excitatory neurotransmitter receptors in the mammalian brain and are activated in a variety of normal neurophysiologic processes. These receptors are heteromeric protein complexes with multiple subunits, each possessing transmembrane regions, and all arranged to form a ligand-gated ion channel. GRIA2 belongs to a family of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate (AMPA) receptors. Each of the members (GRIA14) include flip and flop isoforms generated by alternative RNA splicing. This antibody can recognize both isoforms.
| Application: | Immunofluorescence, Immunohistochemistry, Western Blot |
|---|---|
| Clonality: | Polyclonal |
| Concentration: | 0.25 mg/ml |
| Conjugation: | Unconjugated |
| Host: | Rabbit |
| Immunogen: | Synthetic peptide (15-aa) derived from the N-terminal extracellular region of mouse GRIA2 protein |
| Isotype: | IgG |
| Purification: | Affinity Chromatography |
| Reactivity: | Human, Mouse, Rat |
| Species Homology: | Synthetic peptide sequence is identical to rat sequence (showing 93.3% homology to human sequence) |
| Storage: | -20°C |
| Storage Buffer: | PBS, pH 7.2, 0.1% Sodium Azide |