ILDR1 (Angulin-2) Antibody
Description
Anti-ILDR1 (Angulin-2) antibody is validated on mouse tissue and can be used for immunofluorescence labeling, IHC, or western blot of materials from rodent and human tissues. ILDR1, which stands for immunoglobulin [Ig]-like domain-containing receptor 1, also known as angulin-2, belongs to the angulin protein family, which makes the tricellular tight junction in epithelium or endothelium. ILDR1 is encoded by the ILDR1 gene in human. ILDR1 has a single transmembrane domain, an amino-terminal extracellular Ig-like domain, and a carboxyl-terminal cytoplasmic domain. ILDR1 is important to make a water impermeable pathway in the epithelium. Mutations in ILDR1 also cause a human inherited deafness disease known as DFNB42.
| Application: | Immunofluorescence, Immunohistochemistry, Western Blot |
|---|---|
| Clonality: | Polyclonal |
| Concentration: | 0.25 mg/ml |
| Conjugation: | Unconjugated |
| Host: | Rabbit |
| Immunogen: | Synthetic peptide (13-aa) derived from the C-terminal intracellular region of human ILDR1 protein |
| Isotype: | IgG |
| Purification: | Affinity Chromatography |
| Reactivity: | Human, Mouse, Rat |
| Species Homology: | Synthetic peptide sequence is identical to mouse or rat sequence |
| Storage: | -20°C |
| Storage Buffer: | PBS, pH 7.2, 0.1% Sodium Azide |