Integrin alpha-D (ITGAD or CD11d) Antibody
Description
Anti-Integrin alpha-D (ITGAD or CD11d) antibody is validated on mouse tissue and recommended for immunofluorescence labeling, IHC, or western blot of materials from rodent tissues. Integrins are transmembrane proteins that facilitate cell-extracellular matrix interactions or focal adhesions. Ligands for Integrins include fibronectin, vitronectin, collagen and laminin. An integrin molecule is composed of two protein subunits, alpha and beta. Each subunit consists in an extracellular domain, a single transmembrane domain and a cytoplasmic domain. Integrin subunit alpha D, also known as CD11d, is encoded by the ITGAD gene in human. Integrin alpha-D belongs to the beta-2 integrin family and is involved in the activation and adhesion functions of leukocytes.
| Application: | Immunofluorescence, Immunohistochemistry, Western Blot |
|---|---|
| Clonality: | Polyclonal |
| Concentration: | 0.25 mg/ml |
| Conjugation: | Unconjugated |
| Host: | Rat |
| Immunogen: | Synthetic peptide (16-aa) derived from the C-terminal cytoplasmic region of mouse integrin alpha-D protein |
| Isotype: | IgG |
| Purification: | Affinity Chromatography |
| Reactivity: | Mouse, Rat |
| Species Homology: | Synthetic peptide sequence is identical to rat sequence (showing 31.3% homology to human sequence) |
| Storage: | -20°C |
| Storage Buffer: | PBS, pH 7.2, 0.1% Sodium Azide |