Klotho (KL) Antibody
Catalog-Number:
52100
Storage
-20°C
Description
Anti-Klotho (KL) antibody is validated on mouse tissue and can be used for immunofluorescence labeling, IHC, or western blot of materials from rodent and human tissues. Klotho (KL) or ?-Klotho is encoded by the KL gene in human. Klotho is a type-I membrane protein that is related to ?-glucuronidases. Klotho can exist in a membrane-bound form or a (hormonal) soluble, secreted form. Proteases convert the membrane-bound form into the secreted form. The expression level of Klotho is associated with the development of chronic kidney failure.
| Application: | Immunofluorescence, Immunohistochemistry, Western Blot |
|---|---|
| Clonality: | Polyclonal |
| Concentration: | 0.25 mg/ml |
| Conjugation: | Unconjugated |
| Host: | Rat |
| Immunogen: | Synthetic peptide (19-aa) derived from the N-terminal extracellular region of mouse Klotho protein |
| Isotype: | IgG |
| Purification: | Affinity Chromatography |
| Reactivity: | Human, Mouse, Rat |
| Species Homology: | Synthetic peptide sequence is identical to rat sequence (showing 84.2% homology to human sequence) |
| Storage: | -20°C |
| Storage Buffer: | PBS, pH 7.2, 0.1% Sodium Azide |