LIFR (CD118) Antibody
Description
Anti-LIFR (CD118) antibody is validated on mouse tissue and recommended for immunofluorescence labeling, IHC, or western blot of materials from human and rodent tissues. LIFR, also known as CD118 (Cluster of Differentiation 118), is a receptor protein for leukemia inhibitory factor that is encoded by the LIFR gene in human. LIFR can interact with glycoprotein 130. LIFR has been identified as a breast cancer metastasis suppressor that functions through the Hippo-YAP pathway. Mutations in this gene cause Schwartz-Jampel syndrome type 2, a disease belonging to the group of the bent-bone dysplasias.
Application: | Immunofluorescence, Immunohistochemistry, Western Blot |
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Clonality: | Polyclonal |
Concentration: | 0.25 mg/ml |
Conjugation: | Unconjugated |
Host: | Rat |
Immunogen: | Synthetic peptide (17-aa) derived from the C-terminal cytoplasmic region of human LIFR protein |
Isotype: | IgG |
Purification: | Affinity Chromatography |
Reactivity: | Human, Mouse, Rat |
Species Homology: | Synthetic peptide sequence is identical to mouse or rat sequence |
Storage: | -20°C |
Storage Buffer: | PBS, pH 7.2, 0.1% Sodium Azide |