MKS3 (NPHP11 or Meckelin or TMEM67) Antibody
Catalog-Number:
90103
Storage
-20°C
Description
Anti-MKS3 (NPHP11 or Meckelin or TMEM67) antibody is validated on mouse tissue and recommended for immunofluorescence labeling, IHC, or western blot of materials from rodent and human tissues. Meckel syndrome, type 3 (MKS3) or TMEM67 or Meckelin or NPHP11 is encoded by the TMEM67 gene in human. MKS3 is a membrane protein containing 6 transmembrane domains. MKS3 is localized to the primary cilium functions in centriole migration to the apical membrane and formation of the primary cilium. Mutations in TMEM67 cause Meckel syndrome type 3 (MKS3) and Joubert syndrome type 6 (JBTS6) (OMIM 607361).
| Application: | Immunofluorescence, Immunohistochemistry, Western Blot |
|---|---|
| Clonality: | Polyclonal |
| Concentration: | 0.25 mg/ml |
| Conjugation: | Unconjugated |
| Host: | Rabbit |
| Immunogen: | Synthetic peptide (18-aa) derived from the C-terminal region of mouse MKS3 protein |
| Isotype: | IgG |
| Purification: | Affinity Chromatography |
| Reactivity: | Human, Mouse, Rat |
| Species Homology: | Synthetic peptide sequence is identical to rat sequence (showing 94.4% homology to human sequence) |
| Storage: | -20°C |
| Storage Buffer: | PBS, pH 7.2, 0.1% Sodium Azide |