Nephrocystin-5 (NPHP5 or IQCB1) Antibody
Catalog-Number:
90005
Storage
-20°C
Description
Anti-Nephrocystin-5 (NPHP5 or IQCB1) antibody is validated on mouse tissue and recommended for immunofluorescence labeling, IHC, or western blot of materials from rodent and human tissues. Nephrocystin-5 (NPHP5), also known as IQCB1 (IQ calmodulin-binding motif containing protein 1), is a component of the primary cilium. Nephrocystin-5 is encoded by the IQCB1 gene in human. Nephrocystin-5 can interact with multiple BBS proteins and may participate in the entry of the BBSome complex to the primary cilium. Mutations in Nephrocystin-5 cause renal-retinal Senior-Loken syndrome 5 (SLSN5) (OMIM 609254), which manifests as renal failure and retinitis pigmentosa.
| Application: | Immunofluorescence, Immunohistochemistry, Western Blot |
|---|---|
| Clonality: | Polyclonal |
| Concentration: | 0.25 mg/ml |
| Conjugation: | Unconjugated |
| Host: | Rabbit |
| Immunogen: | Synthetic peptide (15-aa) derived from the N-terminal region of human Nephrocystin-5 protein |
| Isotype: | IgG |
| Purification: | Affinity Chromatography |
| Reactivity: | Human, Mouse, Rat |
| Species Homology: | Synthetic peptide sequence is identical to mouse or rat sequence |
| Storage: | -20°C |
| Storage Buffer: | PBS, pH 7.2, 0.1% Sodium Azide |