OCT4 (OCT3 or POU5F1) Antibody
Description
Anti-OCT4 (OCT3 or POU5F1) antibody is validated on mouse tissue and recommended for immunofluorescence labeling, IHC, or western blot of materials from rodent and human tissues. OCT4 (octamer-binding transcription factor 4), also known as OCT3 or POU5F1 (POU domain, class 5, transcription factor 1), is a protein that is encoded by the POU5F1 gene in human. OCT4 is a transcription factor containing a POU homeodomain and playing a key role in stem cell pluripotency. OCT4 binds to an octamer motif in DNA, a particular sequence of AGTCAAAT to regulate gene expression. OCT4 is one of the transcription factors used to create induced pluripotent stem cells (iPSCs), together with Sox2, Klf4 and c-Myc.
| Application: | Immunofluorescence, Immunohistochemistry, Western Blot |
|---|---|
| Clonality: | Polyclonal |
| Concentration: | 0.25 mg/ml |
| Conjugation: | Unconjugated |
| Host: | Rabbit |
| Immunogen: | Synthetic peptide (13-aa) derived from the N-terminal region of human OCT4 protein |
| Isotype: | IgG |
| Purification: | Affinity Chromatography |
| Reactivity: | Human, Mouse, Rat |
| Species Homology: | Synthetic peptide sequence is identical to mouse or rat sequence |
| Storage: | -20°C |
| Storage Buffer: | PBS, pH 7.2, 0.1% Sodium Azide |