Synemin (SYNM or Desmuslin) Antibody
Catalog-Number:
54711
Storage
-20°C
Description
Anti-Synemin (SYNM or Desmuslin) antibody is validated on mouse tissue and recommended for immunofluorescence labeling, IHC, or western blot of materials from rodent and human tissues. Synemin, also known as desmuslin, is a protein that is encoded by the SYNM gene in human. Synemin is an intermediate filament (IF) family member. It localizes at the Z-disk and has been shown to bind to ?-dystrobrevin, ?-actinin, and desmin to act as a mechanical linker in transmitting force laterally throughout the tissue, especially between the contractile myofibrils and extracellular matrix.
| Application: | Immunofluorescence, Immunohistochemistry, Western Blot |
|---|---|
| Clonality: | Polyclonal |
| Concentration: | 0.25 mg/ml |
| Conjugation: | Unconjugated |
| Host: | Rat |
| Immunogen: | Synthetic peptide (17-aa) derived from the N-terminal region of mouse synemin protein |
| Isotype: | IgG |
| Purification: | Affinity Chromatography |
| Reactivity: | Human, Mouse, Rat |
| Species Homology: | Synthetic peptide sequence is identical to rat sequence (showing 94.1% homology to human sequence) |
| Storage: | -20°C |
| Storage Buffer: | PBS, pH 7.2, 0.1% Sodium Azide |