Trpm5 Antibody
Description
Anti-Trpm5 antibody is validated on mouse tissue and can be used for immunofluorescence labeling, IHC, or western blot of materials from rodent tissues. Transient receptor potential cation channel subfamily M member 5 (Trpm5) is a non-selective cation channel protein that is encoded by the TRPM5 gene in human. Trpm5 permeates Na+, K+, and Cs+ ions equally well, but not Ca2+ ions. Trpm5 is highly temperature-sensitive, and when activated by heat the channel shows a steep increase of inward currents at temperatures between 15 and 35 degrees Celsius. Trpm5 is expressed by sensory neurons, neuroepithelial cells in the taste buds, and beta-cells in the pancreas.
Application: | Immunofluorescence, Immunohistochemistry, Western Blot |
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Clonality: | Polyclonal |
Concentration: | 0.25 mg/ml |
Conjugation: | Unconjugated |
Host: | Rat |
Immunogen: | Synthetic peptide (16-aa) derived from the C-terminal region of mouse Trpm5 protein |
Isotype: | IgG |
Purification: | Affinity Chromatography |
Reactivity: | Mouse, Rat |
Species Homology: | Synthetic peptide sequence is identical to rat sequence (shows 56.3% homology to human sequence) |
Storage: | -20°C |
Storage Buffer: | PBS, pH 7.2, 0.1% Sodium Azide |