VEGFR1 (FLT1) Antibody
Description
Anti-VEGFR1 (FLT1) antibody is validated on mouse tissue and recommended for immunofluorescence labeling, IHC, or western blot of materials from rodent and human tissues. Vascular endothelial growth factor receptor 1 (VEGFR1), also known as fms related receptor tyrosine kinase 1 (FLT1), is encoded by the FLT1 gene in human. VEGFR1 is a receptor tyrosine kinase (RTK) that contains an extracellular ligand-binding region with seven immunoglobulin (Ig)-like domains, a transmembrane domain, and a tyrosine kinase (TK) domain within the cytoplasmic domain. VEGFR1 binds to VEGFR-A, VEGFR-B and placental growth factor and plays an important role in angiogenesis and vasculogenesis. Expression of VEGFR1 is found in vascular endothelial cells, placental trophoblast cells and peripheral blood monocytes.
| Application: | Immunofluorescence, Immunohistochemistry, Western Blot |
|---|---|
| Clonality: | Polyclonal |
| Concentration: | 0.25 mg/ml |
| Conjugation: | Unconjugated |
| Host: | Rat |
| Immunogen: | Synthetic peptide (17-aa) derived from the C-terminal region of mouse VEGFR1 protein |
| Isotype: | IgG |
| Purification: | Affinity Chromatography |
| Reactivity: | Human, Mouse, Rat |
| Species Homology: | Synthetic peptide sequence is identical to rat sequence (showing 94.1% homology to human sequence) |
| Storage: | -20°C |
| Storage Buffer: | PBS, pH 7.2, 0.1% Sodium Azide |