ZO-2 (Tjp2) Antibody
Description
Anti-ZO-2 (Tjp2) antibody is validated on mouse tissue and can be used for immunofluorescence labeling, IHC, or western blot of materials from rodent and human tissues. Zonula occludens-2 (ZO-2), also known as tight junction protein-2 (TJP2) is a 130-kD tight junction peripheral protein encoded by the TJP2 gene in human. ZO-2 contains three PDZ domains, an SRC homology 3 (SH3) domain, and a yeast guanylate kinase homology (GUK) domain. ZO-2 can interact with tight junction integral proteins such as claudins and occludin, as well as ZO-1 and ZO-3. ZO-2 is expressed in a variety of epithelial tissues including the kidney, the intestines, the lung, the liver, the pancreas and more.
| Application: | Immunofluorescence, Immunohistochemistry, Western Blot |
|---|---|
| Clonality: | Polyclonal |
| Concentration: | 0.25 mg/ml |
| Conjugation: | Unconjugated |
| Host: | Rabbit |
| Immunogen: | Synthetic peptide (15-aa) derived from the C-terminal region of mouse ZO-2 protein |
| Isotype: | IgG |
| Purification: | Affinity Chromatography |
| Reactivity: | Human, Mouse, Rat |
| Species Homology: | Synthetic peptide sequence is identical to rat sequence (showing 80% homology to human sequence) |
| Storage: | -20°C |
| Storage Buffer: | PBS, pH 7.2, 0.1% Sodium Azide |