11-beta-HSD1 (HSD11B1) Antibody
BiCell Scientific
SKU:52041-50UL
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About the Target
Build reproducible readouts by using this antibody to examine 11-beta-HSD1 (HSD11B1) across matched sample sets. 11-beta-HSD1 is a regulator within kinase-driven cascades that influence transcriptional and metabolic responses. For comparison-heavy studies, consistent sample handling and normalization help reduce run-to-run drift.
In some datasets and protocols, it is referenced by the gene symbol HSD11B1.
Research Context
When comparing conditions, consistent sample handling and normalization are key for meaningful contrasts. Define inclusion criteria and controls early so replicate sets remain interpretable as the dataset grows.
Consider these angles when interpreting target-level changes:
- localization shifts between cytoplasm, membrane, and nucleus
- condition-to-condition comparisons with matched controls
- time-resolved changes following stimulation or inhibition
- interaction patterns within multi-protein complexes
Variant Considerations
For broad method development, the regular format can help you benchmark target behavior before narrowing to a specific readout style. This matters because epitope exposure and background can vary with preparation and extraction steps. Standardize key parameters so differences reflect biology rather than handling.
If your study spans multiple model systems, it can help to define a shared reference condition for 11-beta-HSD1 so cross-sample contrasts stay meaningful.
If your study spans multiple model systems, it can help to define a shared reference condition for 11-beta-HSD1 so cross-sample contrasts stay meaningful.
With consistent handling, the regular format format can make 11-beta-HSD1 (HSD11B1) comparisons easier to reproduce across runs.
- Targets:
- HSD11B1
- Research Area:
- Cell Signaling • Endocrinology • Metabolism
- Application:
- IF • IHC • WB
- Reactivity:
- Human • Mouse • Rat
- Host:
- Rat
- Clonality:
- Polyclonal
- Isotype:
- IgG
- Immunogen:
- Synthetic peptide (16-aa) derived from the C-terminal region of mouse HSD11B1 protein
- Conjugation:
- Unconjugated
- Purification:
- Affinity Chromatography
- Concentration:
- 0.25 mg/ml
- UniProt:
- P28845
- Homology:
- Synthetic peptide sequence is identical to rat sequence (showing 81.3% homology to human sequence)
- Storage Buffer:
- PBS, pH 7.2, 0.1% Sodium Azide
- Storage Temperature:
- -20°C