2',5'-Dihydroxyacetophenone

1 1

Selleck Chemicals

S9374-25MG

€95,00 EUR
€95,00 EUR
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2',5'-Dihydroxyacetophenone is an inhibitor of NOS and NF-kB and related targets used in studies of JAK-STAT Signaling and NF-kB Signaling and related signaling programs. It is especially relevant in cardiovascular, immunology, and inflammation models, where defined compound exposure can be linked to cytokine-responsive transcriptional signaling and immune regulation and inflammatory transcriptional control and stress-responsive survival signaling.

By inhibiting NOS and NF-kB and related targets, 2',5'-Dihydroxyacetophenone can be used to examine cytokine-responsive transcriptional signaling and immune regulation and inflammatory transcriptional control and stress-responsive survival signaling. The immunomodulator annotation adds relevance to immune-cell activation, cytokine, and mediator assays, together with downstream-response mapping in the same experimental setting. In cardiovascular, immunology, and inflammation models, these readouts can be combined with viability, reporter, localization, biochemical conversion, or morphology endpoints to refine experimental interpretation.

Research Applications

  • Target-focused assays involving NOS and NF-kB and related targets
  • Pathway perturbation studies connected to JAK-STAT Signaling and NF-kB Signaling and related signaling programs
  • Concentration-response inhibition and target-dependence studies
  • Immune-cell activation, cytokine, and mediator assays

Overall, 2',5'-Dihydroxyacetophenone is appropriate when a defined chemical perturbant is needed to connect NOS and NF-kB and related targets with measurable biochemical, transcriptional, electrophysiological, imaging, or phenotypic readouts in cardiovascular, immunology, and inflammation models. This profile is suited to mechanistic follow-up, comparative profiling, and assay optimization under defined exposure conditions.

Targets:
NOS • NF-kB • TNF-alpha • Interleukins
Target Class:
Immunomodulator
Pathways:
JAK-STAT Signaling • NF-kB Signaling • Immune Signaling
Research Area:
Cardiovascular • Immunology • Inflammation
CAS No.:
490-78-8
Molecular Weight:
152.15
Formula:
C₈H₈O₃
SMILES:
CC(=O)C1=C(C=CC(=C1)O)O
Storage Temperature:
-20°C

For Research Use Only. Not intended for diagnostic or therapeutic use.
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