2-APB (2-Aminoethyl Diphenylborinate)

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Selleck Chemicals

S6657-25MG

€144,00 EUR
€144,00 EUR
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2-APB (2-Aminoethyl Diphenylborinate) is an activator of TRP Channels used in studies of Calcium Signaling. In practice, this places the compound in experiments that measure calcium flux, excitability, and secretion-linked signaling in cell signaling and neuroscience models.

By activating TRP Channels, 2-APB (2-Aminoethyl Diphenylborinate) can be used to examine calcium flux, excitability, and secretion-linked signaling. The ion channel annotation adds relevance to electrophysiology, ion-flux, and membrane-potential studies, together with downstream-response mapping in the same experimental setting. In cell signaling and neuroscience models, these readouts can be combined with viability, reporter, localization, biochemical conversion, or morphology endpoints to refine experimental interpretation.

Research Applications

  • Target-focused assays involving TRP Channels
  • Pathway perturbation studies connected to Calcium Signaling
  • Gain-of-function pathway-activation studies
  • Electrophysiology, ion-flux, and membrane-potential studies

Overall, 2-APB (2-Aminoethyl Diphenylborinate) is appropriate when a defined chemical perturbant is needed to connect TRP Channels with measurable biochemical, transcriptional, electrophysiological, imaging, or phenotypic readouts in cell signaling and neuroscience models. This profile is suited to mechanistic follow-up, comparative profiling, and assay optimization under defined exposure conditions.

Targets:
TRP Channels
Target Class:
Ion Channel
Pathways:
Calcium Signaling
Research Area:
Cell Signaling • Neuroscience
CAS No.:
524-95-8
Molecular Weight:
225.09
Formula:
C₁₄H₁₆BNO
SMILES:
B(C1=CC=CC=C1)(C2=CC=CC=C2)OCCN
Storage Temperature:
-20°C

For Research Use Only. Not intended for diagnostic or therapeutic use.
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