2-Ketoglutaric acid (alpha-ketoglutarate)
Selleck Chemicals
SKU:S6237-1G
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2-Ketoglutaric acid (alpha-ketoglutarate) is an inhibitor of Tyrosinase used in studies of Metabolic Signaling. In practice, this places the compound in experiments that measure metabolic regulation, energy sensing, and enzyme-linked homeostasis in developmental biology models.
By inhibiting Tyrosinase, 2-Ketoglutaric acid (alpha-ketoglutarate) can be used to examine metabolic regulation, energy sensing, and enzyme-linked homeostasis. The enzyme annotation adds relevance to enzyme-activity assays, substrate-conversion studies, and mechanism profiling, together with downstream-response mapping in the same experimental setting. In developmental biology models, these readouts can be combined with viability, reporter, localization, biochemical conversion, or morphology endpoints to refine experimental interpretation.
Research Applications
- Target-focused assays involving Tyrosinase
- Pathway perturbation studies connected to Metabolic Signaling
- Concentration-response inhibition and target-dependence studies
- Enzyme-activity assays, substrate-conversion studies, and mechanism profiling
Overall, 2-Ketoglutaric acid (alpha-ketoglutarate) is appropriate when a defined chemical perturbant is needed to connect Tyrosinase with measurable biochemical, transcriptional, electrophysiological, imaging, or phenotypic readouts in developmental biology models. This profile is suited to mechanistic follow-up, comparative profiling, and assay optimization under defined exposure conditions.
- Targets:
- Tyrosinase
- Target Class:
- Enzyme
- Pathways:
- Metabolic Signaling
- Research Area:
- Developmental Biology
- CAS No.:
- 328-50-7
- Molecular Weight:
- 146.10
- Formula:
- C₅H₆O₅
- SMILES:
- C(CC(=O)O)C(=O)C(=O)O
- Storage Temperature:
- -20°C
For Research Use Only. Not intended for diagnostic or therapeutic use.
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