3-Aminobenzamide
Selleck Chemicals
SKU:S1132-5MG
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3-Aminobenzamide is an inhibitor of PARP used in studies of DNA Damage Response and Apoptosis. It is especially relevant in apoptosis, cancer, and dna damage / repair models, where defined compound exposure can be linked to checkpoint activation, DNA repair, and genome-stability control and caspase-associated cell-death signaling and survival decisions.
By inhibiting PARP, 3-Aminobenzamide can be used to examine checkpoint activation, DNA repair, and genome-stability control and caspase-associated cell-death signaling and survival decisions. The enzyme annotation adds relevance to enzyme-activity assays, substrate-conversion studies, and mechanism profiling, together with downstream-response mapping in the same experimental setting. In apoptosis, cancer, and dna damage / repair models, these readouts can be combined with viability, reporter, localization, biochemical conversion, or morphology endpoints to refine experimental interpretation.
Research Applications
- Target-focused assays involving PARP
- Pathway perturbation studies connected to DNA Damage Response and Apoptosis
- Concentration-response inhibition and target-dependence studies
- Enzyme-activity assays, substrate-conversion studies, and mechanism profiling
Overall, 3-Aminobenzamide is appropriate when a defined chemical perturbant is needed to connect PARP with measurable biochemical, transcriptional, electrophysiological, imaging, or phenotypic readouts in apoptosis, cancer, and dna damage / repair models. This profile is suited to mechanistic follow-up, comparative profiling, and assay optimization under defined exposure conditions.
- Targets:
- PARP
- Target Class:
- Enzyme
- Pathways:
- DNA Damage Response • Apoptosis
- Research Area:
- Apoptosis • Cancer • DNA Damage / Repair
- CAS No.:
- 3544-24-9
- Molecular Weight:
- 136.15
- Formula:
- C₇H₈N₂O
- SMILES:
- C1=CC(=CC(=C1)N)C(=O)N
- Storage Temperature:
- -20°C
For Research Use Only. Not intended for diagnostic or therapeutic use.
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