3-Deazaadenosine hydrochloride

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Selleck Chemicals

S0787-5MG

€291,00 EUR
€291,00 EUR
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3-Deazaadenosine hydrochloride is an inhibitor of TNF-alpha used in studies of PI3K-Akt-mTOR Signaling and NF-kB Signaling and related signaling programs. It is especially relevant when investigators need a named chemical input and interpretable readouts connected to growth-factor signaling, survival control, and nutrient-sensing outputs and inflammatory transcriptional control and stress-responsive survival signaling in apoptosis, cancer, and immunology models.

By inhibiting TNF-alpha, 3-Deazaadenosine hydrochloride can be used to examine growth-factor signaling, survival control, and nutrient-sensing outputs and inflammatory transcriptional control and stress-responsive survival signaling. The immunomodulator annotation adds relevance to immune-cell activation, cytokine, and mediator assays, together with downstream-response mapping in the same experimental setting. In apoptosis, cancer, and immunology models, these readouts can be combined with viability, reporter, localization, biochemical conversion, or morphology endpoints to refine experimental interpretation.

Research Applications

  • Target-focused assays involving TNF-alpha
  • Pathway perturbation studies connected to PI3K-Akt-mTOR Signaling and NF-kB Signaling and related signaling programs
  • Concentration-response inhibition and target-dependence studies
  • Immune-cell activation, cytokine, and mediator assays

Overall, 3-Deazaadenosine hydrochloride is appropriate when a defined chemical perturbant is needed to connect TNF-alpha with measurable biochemical, transcriptional, electrophysiological, imaging, or phenotypic readouts in apoptosis, cancer, and immunology models. This profile is suited to mechanistic follow-up, comparative profiling, and assay optimization under defined exposure conditions.

Targets:
TNF-alpha
Target Class:
Immunomodulator
Pathways:
PI3K-Akt-mTOR Signaling • NF-kB Signaling • Immune Signaling
Research Area:
Apoptosis • Cancer • Immunology • Inflammation
CAS No.:
86583-19-9
Molecular Weight:
302.71
Formula:
C₁₁H₁₅ClN₄O₄
SMILES:
C1=CN=C(C2=C1N(C=N2)C3C(C(C(O3)CO)O)O)N.Cl
Storage Temperature:
-20°C

For Research Use Only. Not intended for diagnostic or therapeutic use.
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