3-deazaadenosine

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Selleck Chemicals

SKU:S6835-5MG

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3-deazaadenosine is an inhibitor of Histamine Receptors used in studies of Viral Entry / Replication and GPCR Signaling and related signaling programs. It is especially relevant in cancer, epigenetics, and inflammation models, where defined compound exposure can be linked to host-pathogen interactions, entry mechanisms, and replication-associated responses and receptor-driven second-messenger signaling and desensitization dynamics.

By inhibiting Histamine Receptors, 3-deazaadenosine can be used to examine host-pathogen interactions, entry mechanisms, and replication-associated responses and receptor-driven second-messenger signaling and desensitization dynamics. The gpcr annotation adds relevance to GPCR pharmacology, ligand-binding, and signaling assays, together with downstream-response mapping in the same experimental setting. In cancer, epigenetics, and inflammation models, these readouts can be combined with viability, reporter, localization, biochemical conversion, or morphology endpoints to refine experimental interpretation.

Research Applications

  • Target-focused assays involving Histamine Receptors
  • Pathway perturbation studies connected to Viral Entry / Replication and GPCR Signaling and related signaling programs
  • Concentration-response inhibition and target-dependence studies
  • GPCR pharmacology, ligand-binding, and signaling assays

Overall, 3-deazaadenosine is appropriate when a defined chemical perturbant is needed to connect Histamine Receptors with measurable biochemical, transcriptional, electrophysiological, imaging, or phenotypic readouts in cancer, epigenetics, and inflammation models. This profile is suited to mechanistic follow-up, comparative profiling, and assay optimization under defined exposure conditions.

Targets:
Histamine Receptors
Target Class:
GPCR
Pathways:
Viral Entry / Replication • GPCR Signaling • Neurotransmission
Research Area:
Cancer • Epigenetics • Inflammation • Infectious Disease
CAS No.:
6736-58-9
Molecular Weight:
266.25
Formula:
C₁₁H₁₄N₄O₄
SMILES:
NC1=C2N=C[N](C3OC(CO)C(O)C3O)C2=CC=N1
InChIKey:
DBZQFUNLCALWDY-WGNDUZGJSA-N
PubChem:
23190
Storage Temperature:
-20°C

For Research Use Only. Not intended for diagnostic or therapeutic use.
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