5'-Deoxy-5'- (methylthio)adenosine

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Selleck Chemicals

SKU:E4032-25MG

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5'-Deoxy-5'- (methylthio)adenosine is an agonist of Adenosine Receptors used in studies of GPCR Signaling. In practice, this places the compound in experiments that measure receptor-driven second-messenger signaling and desensitization dynamics in cardiovascular and inflammation models.

By activating Adenosine Receptors, 5'-Deoxy-5'- (methylthio)adenosine can be used to examine receptor-driven second-messenger signaling and desensitization dynamics. The gpcr annotation adds relevance to GPCR pharmacology, ligand-binding, and signaling assays, together with downstream-response mapping in the same experimental setting. In cardiovascular and inflammation models, these readouts can be combined with viability, reporter, localization, biochemical conversion, or morphology endpoints to refine experimental interpretation.

Research Applications

  • Target-focused assays involving Adenosine Receptors
  • Pathway perturbation studies connected to GPCR Signaling
  • Agonist-response and downstream signaling studies
  • GPCR pharmacology, ligand-binding, and signaling assays

Overall, 5'-Deoxy-5'- (methylthio)adenosine is appropriate when a defined chemical perturbant is needed to connect Adenosine Receptors with measurable biochemical, transcriptional, electrophysiological, imaging, or phenotypic readouts in cardiovascular and inflammation models. This profile is suited to mechanistic follow-up, comparative profiling, and assay optimization under defined exposure conditions.

Targets:
Adenosine Receptors
Target Class:
GPCR
Pathways:
GPCR Signaling
Research Area:
Cardiovascular • Inflammation
CAS No.:
2457-80-9
Molecular Weight:
297.34
Formula:
C₁₁H₁₅N₅O₃S
SMILES:
CSC[C@@H]1O[C@@H](n2cnc3c(N)ncnc32)[C@H](O)[C@H]1O
InChIKey:
WUUGFSXJNOTRMR-WOIOKPISSA-N
PubChem:
439176
Storage Temperature:
-20°C

For Research Use Only. Not intended for diagnostic or therapeutic use.
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