5'-Deoxy-5'- (methylthio)adenosine
Selleck Chemicals
SKU:E4032-25MG
Couldn't load pickup availability

5'-Deoxy-5'- (methylthio)adenosine is an agonist of Adenosine Receptors used in studies of GPCR Signaling. In practice, this places the compound in experiments that measure receptor-driven second-messenger signaling and desensitization dynamics in cardiovascular and inflammation models.
By activating Adenosine Receptors, 5'-Deoxy-5'- (methylthio)adenosine can be used to examine receptor-driven second-messenger signaling and desensitization dynamics. The gpcr annotation adds relevance to GPCR pharmacology, ligand-binding, and signaling assays, together with downstream-response mapping in the same experimental setting. In cardiovascular and inflammation models, these readouts can be combined with viability, reporter, localization, biochemical conversion, or morphology endpoints to refine experimental interpretation.
Research Applications
- Target-focused assays involving Adenosine Receptors
- Pathway perturbation studies connected to GPCR Signaling
- Agonist-response and downstream signaling studies
- GPCR pharmacology, ligand-binding, and signaling assays
Overall, 5'-Deoxy-5'- (methylthio)adenosine is appropriate when a defined chemical perturbant is needed to connect Adenosine Receptors with measurable biochemical, transcriptional, electrophysiological, imaging, or phenotypic readouts in cardiovascular and inflammation models. This profile is suited to mechanistic follow-up, comparative profiling, and assay optimization under defined exposure conditions.
- Targets:
- Adenosine Receptors
- Target Class:
- GPCR
- Pathways:
- GPCR Signaling
- Research Area:
- Cardiovascular • Inflammation
- CAS No.:
- 2457-80-9
- Molecular Weight:
- 297.34
- Formula:
- C₁₁H₁₅N₅O₃S
- SMILES:
- CSC[C@@H]1O[C@@H](n2cnc3c(N)ncnc32)[C@H](O)[C@H]1O
- InChIKey:
- WUUGFSXJNOTRMR-WOIOKPISSA-N
- PubChem:
- 439176
- Storage Temperature:
- -20°C
For Research Use Only. Not intended for diagnostic or therapeutic use.
Products may be subject to intellectual property rights.
The purchase of this product does not grant any license for commercial use, manufacturing, or clinical applications. The user is responsible for ensuring compliance with applicable laws and third-party rights.