ABT-239
Selleck Chemicals
SKU:E8015
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ABT-239 is an antagonist of TRP Channels used in studies of Calcium Signaling. It is especially relevant in cell signaling and neuroscience models, where defined compound exposure can be linked to calcium flux, excitability, and secretion-linked signaling.
By blocking TRP Channels, ABT-239 can be used to examine calcium flux, excitability, and secretion-linked signaling. The ion channel annotation adds relevance to electrophysiology, ion-flux, and membrane-potential studies, together with downstream-response mapping in the same experimental setting. In cell signaling and neuroscience models, these readouts can be combined with viability, reporter, localization, biochemical conversion, or morphology endpoints to refine experimental interpretation.
Research Applications
- Target-focused assays involving TRP Channels
- Pathway perturbation studies connected to Calcium Signaling
- Receptor-blockade and ligand-competition studies
- Electrophysiology, ion-flux, and membrane-potential studies
Overall, ABT-239 is appropriate when a defined chemical perturbant is needed to connect TRP Channels with measurable biochemical, transcriptional, electrophysiological, imaging, or phenotypic readouts in cell signaling and neuroscience models. This profile is suited to mechanistic follow-up, comparative profiling, and assay optimization under defined exposure conditions.
- Targets:
- TRP Channels
- Target Class:
- Ion Channel
- Pathways:
- Calcium Signaling
- Research Area:
- Cell Signaling • Neuroscience
- CAS No.:
- 460746-46-7
- Molecular Weight:
- 330.42
- Storage Temperature:
- -20°C
For Research Use Only. Not intended for diagnostic or therapeutic use.
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