Ac-YVAD-cmk

1 1

Selleck Chemicals

S9727-5MG

€285,00 EUR
€285,00 EUR
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Ac-YVAD-cmk is an inhibitor of Interleukins used in studies of JAK-STAT Signaling and Immune Signaling. In practice, this places the compound in experiments that measure cytokine-responsive transcriptional signaling and immune regulation and cytokine-mediated signaling and inflammatory effector responses in immunology and inflammation models.

By inhibiting Interleukins, Ac-YVAD-cmk can be used to examine cytokine-responsive transcriptional signaling and immune regulation and cytokine-mediated signaling and inflammatory effector responses. The immunomodulator annotation adds relevance to immune-cell activation, cytokine, and mediator assays, together with downstream-response mapping in the same experimental setting. In immunology and inflammation models, these readouts can be combined with viability, reporter, localization, biochemical conversion, or morphology endpoints to refine experimental interpretation.

Research Applications

  • Target-focused assays involving Interleukins
  • Pathway perturbation studies connected to JAK-STAT Signaling and Immune Signaling
  • Concentration-response inhibition and target-dependence studies
  • Immune-cell activation, cytokine, and mediator assays

Overall, Ac-YVAD-cmk is appropriate when a defined chemical perturbant is needed to connect Interleukins with measurable biochemical, transcriptional, electrophysiological, imaging, or phenotypic readouts in immunology and inflammation models. This profile is suited to mechanistic follow-up, comparative profiling, and assay optimization under defined exposure conditions.

Targets:
Interleukins
Target Class:
Immunomodulator
Pathways:
JAK-STAT Signaling • Immune Signaling
Research Area:
Immunology • Inflammation
CAS No.:
178603-78-6
Molecular Weight:
540.99
Formula:
C₂₄H₃₃ClN₄O₈
SMILES:
CC(C)C(NC(=O)C(CC1=CC=C(O)C=C1)NC(C)=O)C(=O)NC(C)C(=O)NC(CC(O)=O)C(=O)CCl
Storage Temperature:
-20°C

For Research Use Only. Not intended for diagnostic or therapeutic use.
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The purchase of this product does not grant any license for commercial use, manufacturing, or clinical applications. The user is responsible for ensuring compliance with applicable laws and third-party rights.