ACBI1
Selleck Chemicals
SKU:S9612-5MG
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ACBI1 is a modulator of BET and E3 Ligase used in studies of Apoptosis and Protein Degradation / Proteasome and related signaling programs. It is especially relevant when investigators need a named chemical input and interpretable readouts connected to caspase-associated cell-death signaling and survival decisions and ubiquitin-dependent turnover, proteostasis, and targeted protein degradation in apoptosis, cancer, and epigenetics models.
By modulating BET and E3 Ligase, ACBI1 can be used to examine caspase-associated cell-death signaling and survival decisions and ubiquitin-dependent turnover, proteostasis, and targeted protein degradation. The epigenetic regulator annotation adds relevance to chromatin, epigenetic, and gene-expression profiling, together with downstream-response mapping in the same experimental setting. In apoptosis, cancer, and epigenetics models, these readouts can be combined with viability, reporter, localization, biochemical conversion, or morphology endpoints to refine experimental interpretation.
Research Applications
- Target-focused assays involving BET and E3 Ligase
- Pathway perturbation studies connected to Apoptosis and Protein Degradation / Proteasome and related signaling programs
- Context-dependent response profiling and mechanism comparison
- Chromatin, epigenetic, and gene-expression profiling
Overall, ACBI1 is appropriate when a defined chemical perturbant is needed to connect BET and E3 Ligase with measurable biochemical, transcriptional, electrophysiological, imaging, or phenotypic readouts in apoptosis, cancer, and epigenetics models. This profile is suited to mechanistic follow-up, comparative profiling, and assay optimization under defined exposure conditions.
- Targets:
- BET • E3 Ligase
- Target Class:
- Epigenetic Regulator
- Pathways:
- Apoptosis • Protein Degradation / Proteasome • Epigenetic Regulation
- Research Area:
- Apoptosis • Cancer • Epigenetics • Protein Homeostasis
- CAS No.:
- 2375564-55-7
- Molecular Weight:
- 936.10
- Formula:
- C₄₉H₅₈FN₉O₇S
- SMILES:
- CC1=C(SC=N1)C2=CC(=C(CNC(=O)C3CC(O)CN3C(=O)C(NC(=O)C4(F)CC4)C(C)(C)C)C=C2)OCCOC5=CC=C(CN6CCN(CC6)C7=C(N)N=NC(=C7)C8=C(O)C=CC=C8)C=C5
- Storage Temperature:
- -20°C
For Research Use Only. Not intended for diagnostic or therapeutic use.
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