ACE1 (ACE or CD143) Antibody
BiCell Scientific
SKU:50409-50UL
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Scientific Overview
When you need to examine ACE1 (CD143) with attention to cellular organization, this antibody provides a focused option. ACE1 is a regulator within kinase-driven cascades that influence transcriptional and metabolic responses. Its behavior can reflect changes in differentiation state, stress, or remodeling of cellular architecture.
In some datasets and protocols, it is referenced by the gene symbol CD143.
Research Relevance
When comparing conditions, consistent sample handling and normalization are key for meaningful contrasts. Because regulation can be multi-layered, combining abundance and localization information can sharpen conclusions.
When cell-state transitions occur, this target may change alongside partners in the same compartment or pathway neighborhood.
When building a narrative around the target, it helps to track:
- condition-to-condition comparisons with matched controls
- interaction patterns within multi-protein complexes
- localization shifts between cytoplasm, membrane, and nucleus
Application-Specific Context
If your project spans exploratory questions, the regular version offers a balanced option for establishing baseline signal behavior. Think about how preparation affects epitope accessibility, and interpret patterns alongside morphology and compartment markers as needed.
When interpreting ACE1, consider whether changes track with compartment identity, cell density, or perturbation timing; these factors can influence apparent signal without implying a direct causal link.
If your study spans multiple model systems, it can help to define a shared reference condition for ACE1 so cross-sample contrasts stay meaningful.
Use the regular format variant when your project demands ACE1 (CD143) readouts that respect preparation constraints.
- Targets:
- ACE
- Research Area:
- Cardiovascular • Cell Signaling • Developmental Biology • Immunology
- Application:
- IF • IHC • WB
- Reactivity:
- Human • Mouse • Rat
- Host:
- Rat
- Clonality:
- Polyclonal
- Isotype:
- IgG
- Immunogen:
- Synthetic peptide (16-aa) derived from the N-terminal extracellular region of mouse ACE protein
- Conjugation:
- Unconjugated
- Purification:
- Affinity Chromatography
- Concentration:
- 0.25 mg/ml
- UniProt:
- P12821
- Homology:
- Synthetic peptide sequence is identical to rat sequence (showing 93.8% homology to human sequence)
- Storage Buffer:
- PBS, pH 7.2, 0.1% Sodium Azide
- Storage Temperature:
- -20°C