ADGRA2 (GPR124) Antibody - Western Blot Validated
BiCell Scientific
SKU:31703-WB-50UL
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About the Target
This antibody is suited for researchers who want to analyze ADGRA2 and relate it to cell-state biology. ADGRA2 is a membrane-associated component that helps organize cell-cell contacts and polarity. Its behavior can reflect changes in differentiation state, stress, or remodeling of cellular architecture.
In some datasets and protocols, it is referenced by the gene symbol GPR124.
Research Context
Researchers often monitor junctional targets when studying epithelial integrity, remodeling, and motility. Because regulation can be multi-layered, combining abundance and localization information can sharpen conclusions. Blood-brain barrier models often monitor junction regulation alongside permeability-focused measurements.
Consider these angles when interpreting target-level changes:
- co-localization patterns with cytoskeletal elements
- comparative profiling across cell states or perturbations
- changes in complex assembly with scaffold or adaptor proteins
Variant Considerations
For size-resolved readouts under denaturing conditions, this version helps you focus on expected band patterns and molecular weight regions. This matters because epitope exposure and background can vary with preparation and extraction steps. If you compare conditions, keep processing steps uniform to support clean interpretation.
For challenging targets, pairing ADGRA2 measurements with a second marker can clarify whether differences arise from regulation, redistribution, or shifts in cell composition within the sample.
For challenging targets, pairing ADGRA2 measurements with a second marker can clarify whether differences arise from regulation, redistribution, or shifts in cell composition within the sample.
Use the denaturing-format variant when your project demands ADGRA2 readouts that respect preparation constraints.
- Targets:
- ADGRA2
- Research Area:
- Cardiovascular • Cell Signaling • Developmental Biology • Neuroscience
- Application:
- WB
- Reactivity:
- Human • Mouse • Rat
- Host:
- Rat
- Clonality:
- Polyclonal
- Isotype:
- IgG
- Immunogen:
- Synthetic peptide (12-aa) derived from the C-terminal cytoplasmic region of human ADGRA2 protein
- Conjugation:
- Unconjugated
- Purification:
- Affinity Chromatography
- Concentration:
- 0.25 mg/ml
- UniProt:
- Q96PE1
- Homology:
- Synthetic peptide sequence is identical to mouse or rat sequence
- Storage Buffer:
- PBS, pH 7.2, 0.1% Sodium Azide
- Storage Temperature:
- -20°C