Afuresertib hydrochloride

1 1

Selleck Chemicals

E4992-5MG

€193,00 EUR
€193,00 EUR
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Afuresertib hydrochloride is an inhibitor of AKT and AKT1 and related targets used in studies of PI3K-Akt-mTOR Signaling. In practice, this places the compound in experiments that measure growth-factor signaling, survival control, and nutrient-sensing outputs in cancer, cell signaling, and metabolism models.

By inhibiting AKT and AKT1 and related targets, Afuresertib hydrochloride can be used to examine growth-factor signaling, survival control, and nutrient-sensing outputs. The kinase annotation adds relevance to biochemical kinase assays, phospho-signaling studies, and selectivity profiling, together with downstream-response mapping in the same experimental setting. In cancer, cell signaling, and metabolism models, these readouts can be combined with viability, reporter, localization, biochemical conversion, or morphology endpoints to refine experimental interpretation.

Research Applications

  • Target-focused assays involving AKT and AKT1 and related targets
  • Pathway perturbation studies connected to PI3K-Akt-mTOR Signaling
  • Concentration-response inhibition and target-dependence studies
  • Biochemical kinase assays, phospho-signaling studies, and selectivity profiling

Overall, Afuresertib hydrochloride is appropriate when a defined chemical perturbant is needed to connect AKT and AKT1 and related targets with measurable biochemical, transcriptional, electrophysiological, imaging, or phenotypic readouts in cancer, cell signaling, and metabolism models. This profile is suited to mechanistic follow-up, comparative profiling, and assay optimization under defined exposure conditions.

Targets:
AKT • AKT1 • AKT2 • AKT3
Target Class:
Kinase
Pathways:
PI3K-Akt-mTOR Signaling
Research Area:
Cancer • Cell Signaling • Metabolism
CAS No.:
1047645-82-8
Molecular Weight:
463.79
Formula:
C₁₈H₁₇Cl₂FN₄OS·ClH
Storage Temperature:
-20°C

For Research Use Only. Not intended for diagnostic or therapeutic use.
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The purchase of this product does not grant any license for commercial use, manufacturing, or clinical applications. The user is responsible for ensuring compliance with applicable laws and third-party rights.